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Michael J. Mullen

Researcher at St Bartholomew's Hospital

Publications -  120
Citations -  9541

Michael J. Mullen is an academic researcher from St Bartholomew's Hospital. The author has contributed to research in topics: Stenosis & Aortic valve. The author has an hindex of 36, co-authored 110 publications receiving 8633 citations. Previous affiliations of Michael J. Mullen include Barts Health NHS Trust & University College Hospital.

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Prospective Study of Heart Rate Variability and Mortality in Chronic Heart Failure Results of the United Kingdom Heart Failure Evaluation and Assessment of Risk Trial (UK-Heart)

TL;DR: CHF is associated with autonomic dysfunction, which can be quantified by measuring HRV, and a reduction in SDNN identifies patients at high risk of death and is a better predictor of death due to progressive heart failure than other conventional clinical measurements.
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Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication.

TL;DR: Exercise capacity is depressed in ACHD patients (even in allegedly asymptomatic patients) on a par with chronic heart failure subjects and is related to the frequency and duration of hospitalization.
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Mental Stress Induces Transient Endothelial Dysfunction in Humans

TL;DR: These findings suggest that brief episodes of mental stress, similar to those encountered in everyday life, may cause transient endothelial dysfunction in healthy young individuals and might represent a mechanistic link between mental stress and atherogenesis.
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Acute systemic inflammation impairs endothelium-dependent dilatation in humans.

TL;DR: S typhi vaccine generates a mild inflammatory reaction associated with temporary but profound dysfunction of the arterial endothelium in both resistance and conduit vessels to both physical and pharmacological dilator stimuli, which might explain the association between infection and inflammation and the enhanced risk of an acute cardiovascular event.