M
Michael L. Smith
Researcher at University of North Texas Health Science Center
Publications - 72
Citations - 2847
Michael L. Smith is an academic researcher from University of North Texas Health Science Center. The author has contributed to research in topics: Blood pressure & Baroreflex. The author has an hindex of 33, co-authored 72 publications receiving 2659 citations. Previous affiliations of Michael L. Smith include Cardiovascular Institute Hospital & Case Western Reserve University.
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Journal ArticleDOI
Human muscle sympathetic neural and haemodynamic responses to tilt following spaceflight.
Benjamin D. Levine,James A. Pawelczyk,Andrew C. Ertl,Andrew C. Ertl,James F. Cox,Julie H. Zuckerman,André Diedrich,Italo Biaggioni,Chester A. Ray,Michael L. Smith,Satoshi Iwase,Mitsuru Saito,Yoshiki Sugiyama,Tadaaki Mano,Rong Zhang,Ken-ichi Iwasaki,Lynda D. Lane,Jay C. Buckey,William H. Cooke,F. Baisch,David Robertson,Dwain L. Eckberg,C. Gunnar Blomqvist +22 more
TL;DR: It is concluded that after 16 days of spaceflight, muscle sympathetic nerve responses to upright tilt are normal, and left ventricular stroke volume and Muscle sympathetic nerve activity suggested that sympathetic responses were appropriate for the haemodynamic challenge of upright tilt and were unaffected by spaceflight.
Journal ArticleDOI
Biventricular Pacing Decreases Sympathetic Activity Compared With Right Ventricular Pacing in Patients With Depressed Ejection Fraction
Mohamed H. Hamdan,Mohamed H. Hamdan,Jason Zagrodzky,Jose A. Joglar,Clifford J Sheehan,Karthik Ramaswamy,Jeffrey F. Erdner,Richard L. Page,Michael L. Smith +8 more
TL;DR: LV-based pacing results in improved hemodynamics and a decrease in SNA compared with RV pacing in patients with LV dysfunction regardless of the QRS duration.
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Intermittent hypoxia: Cause of or therapy for systemic hypertension?
Tatiana V. Serebrovskaya,Eugenia B. Manukhina,Michael L. Smith,H. Fred Downey,Robert T. Mallet +4 more
TL;DR: The pertinent literature is reviewed in an attempt to reconcile the divergent effects of intermittent hypoxia therapy and obstructive sleep apnea on hypertension, with special emphasis on research conducted in the nations of the former Soviet Union.
Journal ArticleDOI
Hypoxia-mediated prolonged elevation of sympathetic nerve activity after periods of intermittent hypoxic apnea.
TL;DR: The hypothesis that short-term exposure to intermittent hypoxic apnea results in sustained elevation of MSNA and that hypoxia is the primary mediator of this response is supported.
Journal ArticleDOI
Effect of Atrial Fibrillation and an Irregular Ventricular Response on Sympathetic Nerve Activity in Human Subjects
Stephen L. Wasmund,Jian Ming Li,Richard L. Page,Jose A. Joglar,Robert C. Kowal,Michael L. Smith,Mohamed H. Hamdan +6 more
TL;DR: Induced AF results in a significant increase in SNA, which is in part attributable to the irregular ventricular response, which suggests that restoring NSR or regularity might be beneficial, particularly in patients with heart failure.