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Michael Lukas

Researcher at University of Regensburg

Publications -  24
Citations -  1956

Michael Lukas is an academic researcher from University of Regensburg. The author has contributed to research in topics: Vasopressin & Olfactory bulb. The author has an hindex of 13, co-authored 23 publications receiving 1691 citations.

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Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice

TL;DR: The data provide the first evidence that nasally applied OXT indeed reaches behaviorally relevant brain areas, and this uptake is paralleled by changes in plasma OXT.
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The Neuropeptide Oxytocin Facilitates Pro-Social Behavior and Prevents Social Avoidance in Rats and Mice

TL;DR: The data indicate that the basal activity of the endogenous brain OT system is sufficient to promote natural occurring social preference in rodents while synthetic OT shows potential to reverse stress-induced social avoidance and might thus be of use for treating social phobia and social dysfunction in humans.
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Maternal separation interferes with developmental changes in brain vasopressin and oxytocin receptor binding in male rats

TL;DR: Age-dependent changes in V(1A)-R and OT-R binding are likely associated with the maturation of behaviors, such as sexual and aggressive behaviors, while disruption of these changes by MS might contribute to previously observed changes in social behaviors after MS.
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Oxytocin mediates rodent social memory within the lateral septum and the medial amygdala depending on the relevance of the social stimulus: male juvenile versus female adult conspecifics

TL;DR: Results indicate that brain OXT is a critical mediator of social memory in male rodents and that, depending on the biological relevance of the social stimulus, distinct brain regions are recruited to mediate its effects.
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Distinct correlations of vasopressin release within the lateral septum and the bed nucleus of the stria terminalis with the display of intermale aggression.

TL;DR: Although challenging the general view that central AVP release enhances intermale aggression in rodents, the data support a model in which AVP coordinates a range of social behaviors by eliciting region-specific effects.