S
Stefan O. Reber
Researcher at University of Ulm
Publications - 87
Citations - 3390
Stefan O. Reber is an academic researcher from University of Ulm. The author has contributed to research in topics: Corticosterone & Medicine. The author has an hindex of 30, co-authored 76 publications receiving 2831 citations. Previous affiliations of Stefan O. Reber include University of Regensburg & University of Bayreuth.
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Journal ArticleDOI
The Neuropeptide Oxytocin Facilitates Pro-Social Behavior and Prevents Social Avoidance in Rats and Mice
Michael Lukas,Iulia Toth,Stefan O. Reber,David A. Slattery,Alexa H. Veenema,Alexa H. Veenema,Inga D. Neumann +6 more
TL;DR: The data indicate that the basal activity of the endogenous brain OT system is sufficient to promote natural occurring social preference in rodents while synthetic OT shows potential to reverse stress-induced social avoidance and might thus be of use for treating social phobia and social dysfunction in humans.
Journal ArticleDOI
Adrenal insufficiency and colonic inflammation after a novel chronic psycho-social stress paradigm in mice : Implications and mechanisms
Stefan O. Reber,L. Birkeneder,Alexa H. Veenema,Florian Obermeier,Werner Falk,Rainer H. Straub,Inga D. Neumann +6 more
TL;DR: Chronic exposure to CSC alters relevant neuronal, neuroendocrine and immune functions that could be directly or indirectly involved in the damage of the histological integrity of the colon comparable with that seen during the development of colitis.
Journal ArticleDOI
Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice
Stefan O. Reber,Philip H. Siebler,Nina C. Donner,James T. Morton,David G. Smith,Jared M. Kopelman,Kenneth R. Lowe,Kristen J. Wheeler,James H. Fox,James E. Hassell,Benjamin N. Greenwood,Charline Jansch,Anja Lechner,Dominic Schmidt,Nicole Uschold-Schmidt,Andrea M. Füchsl,Dominik Langgartner,Frederick R. Walker,Matthew W. Hale,Gerardo Lopez Perez,Will Van Treuren,Antonio Gonzalez,Andrea L. Halweg-Edwards,Monika Fleshner,Charles L. Raison,Graham A. W. Rook,Shyamal D. Peddada,Rob Knight,Christopher A. Lowry +28 more
TL;DR: It is shown that stress disrupts the homeostatic relationship between the microbiota and the host, resulting in exaggerated inflammation, which provides a framework for developing microbiome- and immunoregulation-based strategies for prevention of stress-related pathologies.
Journal ArticleDOI
Dose-dependent effects of chronic central infusion of oxytocin on anxiety, oxytocin receptor binding and stress-related parameters in mice
TL;DR: A deeper understanding of long-lasting treatment effects is required before OXT can be considered for long-term therapeutic use for the treatment of psychopathologies such as autism, schizophrenia or anxiety-disorders.
Journal ArticleDOI
The Microbiota, Immunoregulation, and Mental Health: Implications for Public Health.
Christopher A. Lowry,David G. Smith,Philip H. Siebler,Dominic Schmidt,Christopher E. Stamper,James E. Hassell,Paula S. M. Yamashita,James H. Fox,Stefan O. Reber,Lisa A. Brenner,Andrew J. Hoisington,Teodor T. Postolache,Kerry A. Kinney,Dante Marciani,Mark Hernandez,Sian M. J. Hemmings,Stefanie Malan-Müller,Kenneth P. Wright,Rob Knight,Charles L. Raison,Graham A. W. Rook +20 more
TL;DR: Though findings are encouraging, significant human subjects’ research is required to evaluate the potential impact of Old Friends, including environmental microbial inputs, on biological signatures and clinically meaningful mental health prevention and intervention outcomes.