M
Michael R. Chicoine
Researcher at Washington University in St. Louis
Publications - 164
Citations - 5447
Michael R. Chicoine is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Glioma & Meningioma. The author has an hindex of 40, co-authored 153 publications receiving 4619 citations. Previous affiliations of Michael R. Chicoine include Barnes-Jewish Hospital & St. Louis Children's Hospital.
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Journal ArticleDOI
Clinical Features and Outcome in North American Adults With Moyamoya Phenomenon
Christopher L. Hallemeier,Keith M. Rich,Robert L. Grubb,Michael R. Chicoine,Christopher J. Moran,DeWitte T. Cross,Gregory J. Zipfel,Ralph G. Dacey,Colin P. Derdeyn +8 more
TL;DR: Moyamoya phenomenon in North American adults is associated with a high risk of recurrent stroke, particularly those with bilateral involvement and ischemic symptoms, and data suggest a potential benefit with surgery if diagnosis could be made earlier.
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Isolation and characterization of human malignant glioma cells from histologically normal brain
TL;DR: Tumor cells were cultured from histologically normal brain acquired from a distance greater than 4 cm from the gross tumor, indicating the relative insensitivity of standard histopathological identification of invasive glioma cells (and hence the inadequacy of frozen-section evaluation of resection margins).
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Integrative genomic analysis identifies NDRG2 as a candidate tumor suppressor gene frequently inactivated in clinically aggressive meningioma.
Eriks A. Lusis,Mark A. Watson,Michael R. Chicoine,Meghan Lyman,Peter Roerig,Guido Reifenberger,David H. Gutmann,Arie Perry +7 more
TL;DR: The findings highlight the utility of combining genomic, epigenetic, and expression data to identify clinically significant tumor biomarkers, and suggest that NDRG2 expression will be a useful and functionally relevant biomarker to predict aggressive behavior in patients with meningioma.
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Preoperative sensorimotor mapping in brain tumor patients using spontaneous fluctuations in neuronal activity imaged with functional magnetic resonance imaging: initial experience.
Dongyang Zhang,James M. Johnston,Michael D. Fox,Eric C. Leuthardt,Robert L. Grubb,Michael R. Chicoine,Matthew D. Smyth,Abraham Z. Snyder,Marcus E. Raichle,Joshua S. Shimony +9 more
TL;DR: Resting-state correlation mapping is a promising tool for reliable functional localization of eloquent cortex and compares well with “gold standard” cortical stimulation mapping and offers several advantages compared with conventional motor mapping fMRI.
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Assessment of brain tumor cell motility in vivo and in vitro
TL;DR: Subpopulations of cells were created by clonal amplification of cells that had migrated most rapidly to the dish periphery and, although morphologically indistinguishable when compared to the original cell line, these subpopulations demonstrated significantly increased motility.