M
Michael W. Clarke
Researcher at University of Western Australia
Publications - 73
Citations - 1506
Michael W. Clarke is an academic researcher from University of Western Australia. The author has contributed to research in topics: Vitamin D and neurology & vitamin D deficiency. The author has an hindex of 18, co-authored 69 publications receiving 1109 citations. Previous affiliations of Michael W. Clarke include Royal Perth Hospital & Australian Research Council.
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Vitamin E in human health and disease.
TL;DR: In vitro studies performed in human cell cultures and animal models suggest that vitamin E might increase the hepatic production of cytochrome P450s and MDR1, which could potentially lower the efficacy of any drug metabolized by CYP3A4 or MDR 1 by vitamin E.
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The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
Natalie C. Ward,Jason H Y Wu,Michael W. Clarke,Ian B. Puddey,Valerie Burke,Kevin D. Croft,Jonathan M. Hodgson +6 more
TL;DR: Treatment with either α- or mixed tocopherols significantly increased BP, pulse pressure and heart rate in individuals with type 2 diabetes, but had no effect on urinary F2-isoprostanes.
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Optimized 25-hydroxyvitamin D analysis using liquid–liquid extraction with 2D separation with LC/MS/MS detection, provides superior precision compared to conventional assays
TL;DR: A new 2 dimensional (2D) ultra performance liquid chromatography (UPLC) separation coupled tandem mass spectrometry (MS/MS) detection to accurately quantitate 25(OH)D3, epi-25-hydroxyvitamin D3, and 25( OH)D2 in adults and children, requiring only 50 μL of human serum.
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Monitoring of intra-operative nociception: Skin conductance and surgical stress index versus stress hormone plasma levels
Thomas Ledowski,Elaine M. Pascoe,B. Ang,T. Schmarbeck,Michael W. Clarke,C. Fuller,Vimal Kapoor +6 more
TL;DR: Surgical Stress Index, heart rate and blood pressure, but not the ‘Number of Fluctuations in Skin Conductance’ changed in response to changes in depth of analgesia by showing significant differences between before and after a bolus of fentanyl.
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Growth temperature and genotype both play important roles in sorghum grain phenolic composition
Gangcheng Wu,Stuart K. Johnson,Janet F. Bornman,Sarita Jane Bennett,Michael W. Clarke,Vijaya Singh,Zhongxiang Fang,Zhongxiang Fang +7 more
TL;DR: The results provide new information on the effects of HT on specific polyphenols in various Australian sorghum genotypes, which might be used as a guide to grow high antioxidant Sorghum grains under projected high temperature in the future.