M
Michael Willmann
Researcher at University of Veterinary Medicine Vienna
Publications - 58
Citations - 1508
Michael Willmann is an academic researcher from University of Veterinary Medicine Vienna. The author has contributed to research in topics: Mast cell & Leukemia. The author has an hindex of 20, co-authored 55 publications receiving 1283 citations. Previous affiliations of Michael Willmann include Medical University of Vienna.
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Journal ArticleDOI
Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia.
Harald Herrmann,Irina Sadovnik,Sabine Cerny-Reiterer,Thomas Rülicke,Gabriele Stefanzl,Michael Willmann,Gregor Hoermann,Martin Bilban,Katharina Blatt,Susanne Herndlhofer,Matthias Mayerhofer,Berthold Streubel,Wolfgang R. Sperr,Tessa L. Holyoake,Christine Mannhalter,Peter Valent +15 more
TL;DR: CD26 expression may explain the abnormal extramedullary spread of CML LSC, and inhibition of CD26 may revert abnormal LSC function and support curative treatment approaches in this malignancy.
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Establishment and characterization of a novel canine B-cell line derived from a spontaneously occurring diffuse large cell lymphoma
Barbara C. Rütgen,Sabine E. Hammer,Wilhelm Gerner,Maria Christian,Abigail Guija de Arespacochaga,Michael Willmann,Miriam Kleiter,Ilse Schwendenwein,Armin Saalmüller +8 more
TL;DR: A new B-cell lymphoma cell line CLBL-1 is established from a dog with confirmed stage IV diffuse large cell lymphoma, and the clonality of IgH gene rearrangement was confirmed by sequencing of 16 positive bacterial clones.
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CT features of alveolitis and sinusitis in horses.
Wolfgang Henninger,E. Mairi Frame,Michael Willmann,H. Simhofer,Dieter Malleczek,Sibylle Kneissl,Elisabeth Mayrhofer +6 more
TL;DR: The maxillary bone, however, especially the facial crest, was involved in nearly every horse, being characterized by endosteal sclerosis, thickening, periosteal reaction, and deformation leading to facial swelling in chronic infections.
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Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting
Josef Singer,Marlene Weichselbaumer,Thomas Stockner,Diana Mechtcheriakova,Yury Sobanov,Erika Bajna,Friedrich Wrba,Reinhard Horvat,Johann G. Thalhammer,Michael Willmann,Erika Jensen-Jarolim +10 more
TL;DR: Modeling revealed that human and canine ErbB-1 and ErBB-2 molecules are highly conserved, which opens up perspectives for comparative immunotherapy trials with canine cancer patients.
Journal ArticleDOI
A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection
Rosine Saleh,Ghaith Wedeh,Harald Herrmann,Siham Bibi,Sabine Cerny-Reiterer,Irina Sadovnik,Katharina Blatt,Emir Hadzijusufovic,Emir Hadzijusufovic,Sylvie Jeanningros,Catherine Blanc,Magali Legarff-Tavernier,Elise Chapiro,Florence Nguyen-Khac,Frédéric Subra,Patrick Bonnemye,Patrice Dubreuil,Vanessa Desplat,Hélène Merle-Béral,Michael Willmann,Thomas Rülicke,Peter Valent,Michel Arock +22 more
TL;DR: The data show that KIT D816V is a disease-propagating oncoprotein, but it does not activate MCs to release proinflammatory mediators, which may explain why mediator-related symptoms in SM occur preferentially in the context of a coexisting allergy.