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Michela Sali

Researcher at Catholic University of the Sacred Heart

Publications -  101
Citations -  2316

Michela Sali is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Mycobacterium tuberculosis & Medicine. The author has an hindex of 22, co-authored 82 publications receiving 1606 citations. Previous affiliations of Michela Sali include The Catholic University of America & Agostino Gemelli University Polyclinic.

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The Biology of Mycobacterium Tuberculosis Infection

TL;DR: This review will summarize the recent advancement in the understanding of MtB biology and on the pathogenesis of Mtb infection with emphasis on latent infection, with the change in paradigm of the last few years where the dichotomy between latent and active disease has been reconsidered in favor of a dynamic equilibrium between the host and the bacilli.
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Bloodstream Infections Caused by Extended-Spectrum-β-Lactamase- Producing Escherichia coli: Risk Factors for Inadequate Initial Antimicrobial Therapy

TL;DR: The results underscore the need for a systematic approach to the management of patients with serious infections by ESBL-producing E. coli and highlight the need to identify risk factors for inadequate initial antimicrobial therapy (IIAT), the strongest risk factor for 21-day mortality and the length of hospitalization after BSI onset.
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PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall

TL;DR: The cellular localization of three PE proteins is determined by cell fractionation and immunoelectron microscopy by expressing chimeric epitope‐tagged recombinant proteins in Mycobacterium smegmatis and it is found that PE_PGRS33 is easily extractable by detergents suggesting its localization in the mycobacterial outer membrane.