G
Gennaro De Pascale
Researcher at Catholic University of the Sacred Heart
Publications - 122
Citations - 4559
Gennaro De Pascale is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 28, co-authored 90 publications receiving 2949 citations. Previous affiliations of Gennaro De Pascale include Agostino Gemelli University Polyclinic & The Catholic University of America.
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Journal ArticleDOI
Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study.
Giacomo Grasselli,Giacomo Grasselli,Tommaso Tonetti,Alessandro Protti,Thomas Langer,Massimo Girardis,Giacomo Bellani,John G. Laffey,Gianpaolo Carrafiello,Gianpaolo Carrafiello,Luca Carsana,Chiara Rizzuto,Alberto Zanella,Alberto Zanella,Vittorio Scaravilli,Giacinto Pizzilli,Domenico Luca Grieco,Letizia Di Meglio,Gennaro De Pascale,Ezio Lanza,Francesco Monteduro,Maurizio Zompatori,Claudia Filippini,Franco Locatelli,Maurizio Cecconi,Roberto Fumagalli,Stefano Nava,Jean Louis Vincent,Massimo Antonelli,Arthur S. Slutsky,Antonio Pesenti,Antonio Pesenti,V. Marco Ranieri,Alfredo Lissoni,N Rossi,Amedeo Guzzardella,Carlo Valsecchi,Fabiana Madotto,Francesca Bevilacqua,Marco Di Laudo,Lorenzo Querci,Carmen Seccafico +41 more
TL;DR: Patients with COVID-19-associated ARDS have a form of injury that, in many aspects, is similar to that of those with ARDS unrelated to CO VID-19, who have a reduction in respiratory system compliance together with increased D-dimer concentrations have high mortality rates.
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Efficacy of Ceftazidime-Avibactam Salvage Therapy in Patients With Infections Caused by Klebsiella pneumoniae Carbapenemase-producing K. pneumoniae.
Mario Tumbarello,Enrico Maria Trecarichi,Alberto Corona,Francesco Giuseppe De Rosa,Matteo Bassetti,Cristina Mussini,Francesco Menichetti,Claudio Viscoli,Caterina Campoli,Mario Venditti,Andrea De Gasperi,Alessandra Mularoni,Carlo Tascini,Giustino Parruti,Carlo Pallotto,Simona Sica,Ercole Concia,Rosario Cultrera,Gennaro De Pascale,Alessandro Capone,Spinello Antinori,Silvia Corcione,Elda Righi,Angela Raffaella Losito,Margherita Digaetano,Francesco Amadori,Daniele Roberto Giacobbe,Giancarlo Ceccarelli,E. Mazza,Francesca Raffaelli,Teresa Spanu,Roberto Cauda,Pierluigi Viale +32 more
TL;DR: CAZ-AVI appears to be a promising drug for treatment of severe KPC-Kp infections, especially those involving bacteremia, as well as hospital-acquired pneumonia, and for gram-negative infections with limited treatment options.
Journal ArticleDOI
Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure: The HENIVOT Randomized Clinical Trial.
Domenico Luca Grieco,Luca S Menga,Melania Cesarano,Tommaso Rosà,Savino Spadaro,Maria Maddalena Bitondo,Jonathan Montomoli,Giulia Falò,Tommaso Tonetti,Salvatore Lucio Cutuli,Gabriele Pintaudi,Eloisa Sofia Tanzarella,Edoardo Piervincenzi,Filippo Bongiovanni,Antonio Maria Dell’Anna,Luca Delle Cese,Cecilia Berardi,Simone Carelli,Maria Grazia Bocci,Luca Montini,Giuseppe Bello,Daniele Natalini,Gennaro De Pascale,Gennaro De Pascale,Matteo Velardo,Carlo Alberto Volta,V. Marco Ranieri,Giorgio Conti,Salvatore Maurizio Maggiore,Massimo Antonelli +29 more
TL;DR: In this article, the helmet noninvasive ventilation was compared with high-flow nasal oxygen alone in patients with COVID-19 and moderate to severe hypoxemic respiratory failure.
Journal ArticleDOI
A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality
Matteo Bassetti,Elda Righi,Filippo Ansaldi,Maria Merelli,Trucchi Cecilia,Gennaro De Pascale,Ana Díaz-Martín,Roberto Luzzati,Chiara Rosin,Leonel Lagunes,Enrico Maria Trecarichi,Maurizio Sanguinetti,Brunella Posteraro,José Garnacho-Montero,Assunta Sartor,Jordi Rello,Giorgio Della Rocca,Massimo Antonelli,Mario Tumbarello +18 more
TL;DR: Investigating the determinants of outcome in critically ill patients with septic shock due to candidemia found inadequate source control, inadequate antifungal therapy, and 1-point increments in the APACHE II score as independent variables associated with a higher 30-day mortality rate.
Journal ArticleDOI
High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria
Gennaro De Pascale,Luca Montini,Mariano Alberto Pennisi,Valentina Bernini,Riccardo Maviglia,Giuseppe Bello,Teresa Spanu,Mario Tumbarello,Massimo Antonelli +8 more
TL;DR: TGC was well tolerated at a higher than standard dose in a cohort of critically ill patients with severe infections and in the VAP subgroup the high-dose regimen was associated with better outcomes than conventional administration due to Gram-negative MDR bacteria.