M
Michelle M. T. Jansman
Researcher at Technical University of Denmark
Publications - 17
Citations - 248
Michelle M. T. Jansman is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Chemistry & Hemoglobin. The author has an hindex of 8, co-authored 12 publications receiving 134 citations. Previous affiliations of Michelle M. T. Jansman include University of Twente.
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Recent and prominent examples of nano- and microarchitectures as hemoglobin-based oxygen carriers.
TL;DR: The most recent advances in the assembly of the new generation of HBOCs are featured, with emphasis in two main approaches: the chemical modification of Hb either by cross-linking strategies or by conjugation to other polymers, and the Hb encapsulation strategies, usually in the form of lipidic or polymeric capsules.
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Intracellular Microreactors as Artificial Organelles to Conduct Multiple Enzymatic Reactions Simultaneously.
Maria Godoy-Gallardo,Cédric Labay,Michelle M. T. Jansman,Pramod Kumar Ek,Leticia Hosta-Rigau +4 more
TL;DR: This report on the first microreactor conducting multiple enzymatic reactions simultaneously inside a cell is a considerable step in the field of artificial organelles, which aims to substitute for missing cellular function by replenishing a specific cellular task.
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Haemoglobin-loaded metal organic framework-based nanoparticles camouflaged with a red blood cell membrane as potential oxygen delivery systems
TL;DR: This study presents a novel oxygen carrier system which might find applications as a blood surrogate by entrap Hb within a type of metal organic framework ( MOF)-based nanoparticle (MOF-NP) and shows that the structure and functionality of the encapsulated Hb are well preserved.
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Interaction between drug delivery vehicles and cells under the effect of shear stress
TL;DR: By grouping the discussion in three prominent classes of DDVs (lipidic and polymeric particles as well as inorganic nanoparticles), it is hoped that this review will guide researchers within drug delivery into this exciting field and advance a further implementation of these assay systems within the development ofDDVs.
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Low-Fouling Electrosprayed Hemoglobin Nanoparticles with Antioxidant Protection as Promising Oxygen Carriers.
Xiaoli Liu,Michelle M. T. Jansman,Peter W. Thulstrup,Ana Carina Loureiro Mendes,Ioannis S. Chronakis,Leticia Hosta-Rigau +5 more
TL;DR: A novel HBOCs with high Hb content is fabricated and its potential as an artificial blood substitute is evaluated, demonstrating that the as-prepared Hb-NPs are hemo- and biocompatible while offering antioxidant protection and decreasing the formation of metHb.