Michikazu Nakai

TL;DR: The FRS and recalibrated FRS overestimated the 10-year risk of CHD for the Japanese population and a predictive score including CKD as a coronary risk factor was more accurate for predicting CHD than the original Framingham risk scores in terms of the C-statics and NRI.

TL;DR: It is reported that activating transcription factor (ATF) 4, a transcription factor that is induced downstream of metabolic stresses including endoplasmic reticulum (ER) stress, plays critical roles in SFA-induced interleukin-6 (Il6) expression.

TL;DR: Assessment of clinical characteristics, incidence of systemic embolism (SE), and association between anticoagulation and embolic or bleeding events in patients with first acute myocardial infarction complicated by left ventricular thrombus shows that Appropriate antICOagulation therapy may decrease the incidence of embolic events without increasing the occurrence of bleeding events.

TL;DR: The findings suggest that acute MI patients with CAE are a high-risk subset who might benefit from a pharmacological approach to controlling the coagulation cascade.

TL;DR: Hypertension has significant effect on the residual LTR of stroke among both men and women of middle age, specifically for ischemic stroke in this urban community-based population.