Y
Yoshihiro Miyamoto
Researcher at Foundation for Biomedical Research
Publications - 360
Citations - 11772
Yoshihiro Miyamoto is an academic researcher from Foundation for Biomedical Research. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 48, co-authored 300 publications receiving 9338 citations.
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Journal ArticleDOI
T−786→C Mutation in the 5′-Flanking Region of the Endothelial Nitric Oxide Synthase Gene Is Associated With Coronary Spasm
Masafumi Nakayama,Hirofumi Yasue,Michihiro Yoshimura,Yukio Shimasaki,Kiyotaka Kugiyama,Hisao Ogawa,Takeshi Motoyama,Yoshihiko Saito,Yoshihiro Ogawa,Yoshihiro Miyamoto,Kazuwa Nakao +10 more
TL;DR: Findings strongly suggest that the T-786-->C mutation in the eNOS gene reduces the endothelial NO synthesis and predisposes the patients with the mutation to coronary spasm.
Journal ArticleDOI
An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing.
Jamie D. Kapplinger,David J. Tester,Marielle Alders,Begoña Benito,Myriam Berthet,Josep Brugada,Pedro Brugada,Véronique Fressart,Alejandra Guerchicoff,Carole Harris-Kerr,Shiro Kamakura,Florence Kyndt,Florence Kyndt,Tamara T. Koopmann,Yoshihiro Miyamoto,Ryan Pfeiffer,Guido D. Pollevick,Vincent Probst,Sven Zumhagen,Matteo Vatta,Jeffrey A. Towbin,Wataru Shimizu,Eric Schulze-Bahr,Charles Antzelevitch,Benjamin A. Salisbury,Pascale Guicheney,Arthur A.M. Wilde,Ramon Brugada,Jean-Jacques Schott,Jean-Jacques Schott,Jean-Jacques Schott,Michael J. Ackerman +31 more
TL;DR: Overall, 21% of BrS probands have mutations in SCN5A compared to the 2% to 5% background rate of rare variants reported in healthy control subjects, which may help further distinguish pathogenic mutations from similarly rare but otherwise innocuous ones found in cases.
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Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017.
Makoto Kinoshita,Koutaro Yokote,Hidenori Arai,Mami Iida,Yasushi Ishigaki,Shun Ishibashi,Seiji Umemoto,Genshi Egusa,Hirotoshi Ohmura,Tomonori Okamura,Shinji Kihara,Shinji Koba,Isao Saito,Tetsuo Shoji,Hiroyuki Daida,Kazuhisa Tsukamoto,Juno Deguchi,Seitaro Dohi,Kazushige Dobashi,Hirotoshi Hamaguchi,Masumi Hara,Takafumi Hiro,Sadatoshi Biro,Yoshio Fujioka,Chizuko Maruyama,Yoshihiro Miyamoto,Yoshitaka Murakami,Masayuki Yokode,Hiroshi Yoshida,Hiromi Rakugi,Akihiko Wakatsuki,Shizuya Yamashita +31 more
TL;DR: Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Osaka, Japan department of Medical Statistics, Toho University, Tokyo, Japan Department of Clinical Innovative Medicine, Kyoto University Graduate School of Medicine, Osaka.
Journal ArticleDOI
Clinical Aspects of Type-1 Long-QT Syndrome by Location, Coding Type, and Biophysical Function of Mutations Involving the KCNQ1 Gene
Arthur J. Moss,Wataru Shimizu,Arthur A.M. Wilde,Jeffrey A. Towbin,Wojciech Zareba,Jennifer L. Robinson,Ming Qi,G. Michael Vincent,Michael J. Ackerman,Elizabeth S. Kaufman,Nynke Hofman,Rahul Seth,Shiro Kamakura,Yoshihiro Miyamoto,Ilan Goldenberg,Mark L. Andrews,Scott McNitt +16 more
TL;DR: This genotype–phenotype study indicates that in type-1 LQTS, mutations located in the transmembrane portion of the ion channel protein and the degree of ion channel dysfunction caused by the mutations are important independent risk factors influencing the clinical course of this disorder.
Journal ArticleDOI
Vegetarian Diets and Blood Pressure: A Meta-analysis
Yoko Yokoyama,Yoko Yokoyama,Kunihiro Nishimura,Neal D. Barnard,Neal D. Barnard,Misa Takegami,Makoto Watanabe,Akira Sekikawa,Tomonori Okamura,Yoshihiro Miyamoto +9 more
TL;DR: Consumption of vegetarian diets is associated with lower BP and such diets could be a useful nonpharmacologic means for reducing BP.