M
Michio Imawari
Researcher at University of Tokyo
Publications - 113
Citations - 2233
Michio Imawari is an academic researcher from University of Tokyo. The author has contributed to research in topics: Hepatitis C virus & Cytotoxic T cell. The author has an hindex of 26, co-authored 113 publications receiving 2121 citations. Previous affiliations of Michio Imawari include University of Tsukuba.
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Journal ArticleDOI
Present status of autoimmune hepatitis in Japan - correlating the characteristics with international criteria in an area with a high rate of HCV infection
Gotaro Toda,Mikio Zeniya,Fumitoki Watanabe,Michio Imawari,Kendo Kiyosawa,Mikio Nishioka,Takao Tsuji,Masao Omata +7 more
TL;DR: The International Diagnostic Scoring System for the diagnosis of autoimmune hepatitis worked well in these patients, except for HCV-infected individuals, that is, approximately 10% of the total of AIH patients.
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Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection
Kazumasa Hiroishi,Hiroto Kita,M Kojima,Hiroaki Okamoto,Takashi Moriyama,Takashi Kaneko,Tetsuya Ishikawa,Shin Ohnishi,Tatsuya Aikawa,Naomi Tanaka,Yasuyuki Yazaki,Keiji Mitamura,Michio Imawari +12 more
TL;DR: The results suggest that the HLA B44‐restricted CTLs together with other HCV‐specific CTLS may inhibit the outgrowth of HCV and that high‐ titer infection with HCV may suppress the CTL responses.
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HLA B44–restricted cytotoxic T lymphocytes recognizing an epitope on hepatitis C virus nucleocapsid protein
Hiroto Kita,Takashi Moriyama,Takashi Kaneko,Ichiro Harase,M. Nomura,Hideaki Miura,Ikuo Nakamura,Yoshio Yazaki,Michio Imawari +8 more
TL;DR: The results demonstrate the presence of hepatitis C virus–specific cytotoxic T lymphocytes in the peripheral blood of patients with chronic hepatitis C and provide a strategy to study the role of cytot toxic T lymphocyte in the viral clearance and the pathogenesis of hepatitisC virus infection.
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Androgen and estrogen receptors in hepatocellular carcinoma and in the surrounding noncancerous liver tissue
TL;DR: The results suggest that the expression of androgen receptor may be augmented in association with malignant transformation of hepatocytes while theexpression of estrogen receptors may be rather suppressed and that some of hepatocellular carcinomas may be androgen‐dependent.
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Molecular differences between sporadic serrated and conventional colorectal adenomas.
Kazuo Konishi,Toshiko Yamochi,Reiko Makino,Kazuhiro Kaneko,Taikan Yamamoto,Hisako Nozawa,Atsushi Katagiri,Hiroaki Ito,Kentarou Nakayama,Hidekazu Ota,Keiji Mitamura,Michio Imawari +11 more
TL;DR: In contrast, activation of the Ras/Raf/MEK/MAP kinase cascade by BRAF or KRAS mutation, independently of the genetic instability, may be associated with the progression of about half of SAs.