H
Hiroaki Okamoto
Researcher at Jichi Medical University
Publications - 753
Citations - 41132
Hiroaki Okamoto is an academic researcher from Jichi Medical University. The author has contributed to research in topics: Hepatitis E virus & Hepatitis C virus. The author has an hindex of 94, co-authored 722 publications receiving 39057 citations. Previous affiliations of Hiroaki Okamoto include Gulf Coast Regional Blood Center & Hamamatsu University School of Medicine.
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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes.
Peter Simmonds,Jens Bukh,Christophe Combet,Gilbert Deléage,Nobuyuki Enomoto,Stephen M. Feinstone,Phillippe Halfon,Geneviève Inchauspé,Carla Kuiken,Geert Maertens,Masashi Mizokami,Donald G. Murphy,Hiroaki Okamoto,Jean-Michel Pawlotsky,François Penin,Erwin Sablon,Tadasu Shin-I,Lieven Stuyver,Heinz-Jürgen Thiel,Sergei Viazov,Amy J. Weiner,Anders Widell +21 more
TL;DR: These proposals provide the framework by which the HCV databases store and provide access to data on HCV, which will internationally coordinate the assignment of new genotypes and subtypes in the future.
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Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources.
Hiroaki Okamoto,Yasushi Sugiyama,Shunichi Okada,Kiyohiko Kurai,Yoshihiro Akahane,Yoshiki Sugai,Takeshi Tanaka,Koei Sato,Fumio Tsuda,Yuzo Miyakawa,Makoto Mayumi +10 more
TL;DR: HCV types were identical in mother and baby in each of two examples of perinatal transmission, and were also identical in donor and recipient in a case of accidental needle exposure.
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A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology.
Tsutomu Nishizawa,Hiroaki Okamoto,Keiko Konishi,Hiroshi Yoshizawa,Yuzo Miyakawa,Makoto Mayumi +5 more
TL;DR: Results indicate that TTV would be a novel DNA virus with a possible capacity to induce posttransfusion non-A to G hepatitis.
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Typing Hepatitis B Virus by Homology in Nucleotide Sequence: Comparison of Surface Antigen Subtypes
Hiroaki Okamoto,Fumio Tsuda,Hiroshi Sakugawa,Retno I. Sastrosoewignjo,Mitsunobu Imai,Yuzo Miyakawa,Makoto Mayumi +6 more
TL;DR: The results indicate that the four major antigenically defined subtypes of envelope polypeptide do not reflect true genotypic variation of HBV and can be induced by an A----G point mutation at nucleotides 365 and 479 in the S gene.
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Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes.
Hiroaki Okamoto,Kiyohiko Kurai,Shunichi Okada,Kayoko Yamamoto,Hisao Lizuka,Takeshi Tanaka,Satoko Fukuda,Fumio Tsuda,Shunji Mishiro +8 more
TL;DR: A proposed phylogenetic tree of HCV, with a fourth branch represented by HC-J8, allowed a classification of all HCV isolates whose complete or partial sequences are now known and suggests that all or most HCV genome sequences will fall into one of the proposed four types.