M
Michiyo Koyanagi
Researcher at Kyoto University
Publications - 9
Citations - 4057
Michiyo Koyanagi is an academic researcher from Kyoto University. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 7, co-authored 9 publications receiving 3899 citations.
Papers
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Journal ArticleDOI
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
Masato Nakagawa,Michiyo Koyanagi,Koji Tanabe,Kazutoshi Takahashi,Tomoko Ichisaka,Takashi Aoi,Keisuke Okita,Yuji Mochiduki,Nanako Takizawa,Shinya Yamanaka +9 more
TL;DR: A modified protocol for the generation of iPS cells that does not require the Myc retrovirus is described and, with this protocol, significantly fewer non-iPS background cells are obtained, and theiPS cells generated were consistently of high quality.
Journal ArticleDOI
Variation in the safety of induced pluripotent stem cell lines
Kyoko Miura,Yohei Okada,Takashi Aoi,Aki Okada,Kazutoshi Takahashi,Keisuke Okita,Masato Nakagawa,Michiyo Koyanagi,Koji Tanabe,Mari Ohnuki,Daisuke Ogawa,Eiji Ikeda,Hideyuki Okano,Shinya Yamanaka +13 more
TL;DR: This study evaluated the teratoma-forming propensity of secondary neurospheres generated from 36 mouse induced pluripotent stem (iPS) cell lines derived in 11 different ways, which correlated with the persistence of undifferentiated cells.
Patent
Efficient method for nuclear reprogramming
Shinya Yamanaka,Michiyo Koyanagi +1 more
TL;DR: In this paper, a method of preparing induced pluripotent stem cells, comprising a nuclear reprogramming step with a nuclear re-programming factor in the presence of miRNA, was proposed.
Journal ArticleDOI
Centrosomal P4.1-associated Protein Is a New Member of Transcriptional Coactivators for Nuclear Factor-κB
TL;DR: A yeast two-hybrid screening using the N-terminal domain of the p65 subunit of NF-κB as bait and isolated centrosomal P4.1-associated protein (CPAP) as a candidate for a RelA-associating partner suggests that CPAP functions as a coactivator of NF -κB-mediated transcription.
Patent
Effective nucleus initialization method
Shinya Yamanaka,Michiyo Koyanagi +1 more
TL;DR: In this article, a method of effectively producing artificial pluripotent stem cells which comprises the step of conducting nucleus initialization by using a nucleus initialization factor in the presence of an miRNA was proposed.