M
Miho Akimoto
Researcher at Teikyo University
Publications - 24
Citations - 1944
Miho Akimoto is an academic researcher from Teikyo University. The author has contributed to research in topics: Pancreatic cancer & Cancer cell. The author has an hindex of 14, co-authored 22 publications receiving 1663 citations. Previous affiliations of Miho Akimoto include Shimane University.
Papers
More filters
Journal ArticleDOI
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.
Kaori Ishikawa,Kaori Ishikawa,Keizo Takenaga,Miho Akimoto,Nobuko Koshikawa,Aya Yamaguchi,Hirotake Imanishi,Kazuto Nakada,Yoshio Honma,Jun-Ichi Hayashi +9 more
TL;DR: It is indicated that mtDNA mutations can contribute to tumor progression by enhancing the metastatic potential of tumor cells by using cytoplasmic hybrid technology.
Journal ArticleDOI
Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death.
TL;DR: It is demonstrated that ginger extract has potent anticancer activity against pancreatic cancer cells by inducing ROS-mediated autosis and warrants further investigation in order to develop an efficacious candidate drug.
Journal ArticleDOI
Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment.
TL;DR: In this paper, the expression level of sST2, a soluble form of the IL-33 receptor (ST2L), is inversely associated with the malignant growth of colorectal cancer.
Journal ArticleDOI
Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells
Atsuko Kasahara,Kaori Ishikawa,Makiko Yamaoka,Masahito Ito,Naoki Watanabe,Miho Akimoto,Akitsugu Sato,Kazuto Nakada,Hitoshi Endo,Yoko Suda,Shinichi Aizawa,Jun-Ichi Hayashi +11 more
TL;DR: Chimeric mice and mito-mice carrying rat mtDNAs were not obtained, suggesting that significant respiration defects or some deficits induced by rat mt DNAs in mouse ES cells prevented their differentiation to generate mice carrying ratmtDNAs.
Journal ArticleDOI
Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells.
Yoshihide Shimojo,Miho Akimoto,Tsunehiro Hisanaga,Tsuneo Tanaka,Yoshitsugu Tajima,Yoshio Honma,Keizo Takenaga +6 more
TL;DR: It is demonstrated that attenuation of ROS by antioxidants suppresses hypoxia-induced EMT and metastatic phenotype, suggesting that antioxidants may be of therapeutic value in treating pancreatic cancers.