M
Mikko P. Laakso
Researcher at University of Eastern Finland
Publications - 40
Citations - 9387
Mikko P. Laakso is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Entorhinal cortex & Hippocampus. The author has an hindex of 34, co-authored 40 publications receiving 8954 citations.
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Journal ArticleDOI
Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study.
Miia Kivipelto,Eeva-Liisa Helkala,Mikko P. Laakso,Tuomo Hänninen,Merja Hallikainen,Kari Alhainen,Hilkka Soininen,Jaakko Tuomilehto,Aulikki Nissinen +8 more
TL;DR: Raised systolic blood pressure and high serum cholesterol concentration, and in particular the combination of these risks, in midlife increase the risk of Alzheimer's disease in later life.
Journal Article
MR volumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices.
Ricardo Insausti,K Juottonen,Hilkka Soininen,A. M. Insausti,Kaarina Partanen,Pauli Vainio,Mikko P. Laakso,Asla Pitkänen +7 more
TL;DR: The method provides a tool by which to measure volumes of the entorhinal, perirhinal and temporopolar cortices on coronal MR images and there were no differences between men and women in the volumes of any of the three cortices.
Journal ArticleDOI
Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study
Miia Kivipelto,Eeva-Liisa Helkala,T. Hänninen,Mikko P. Laakso,Merja Hallikainen,Kari Alhainen,H. Soininen,J. Tuomilehto,Aulikki Nissinen +8 more
TL;DR: Data point to a role for midlife vascular risk factors in the development of MCI in late life, which has been considered as a predictor of AD.
Journal ArticleDOI
Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease
Antao Du,Norbert Schuff,Norbert Schuff,D. L. Amend,Mikko P. Laakso,Y. Y. Hsu,William J. Jagust,Kristine Yaffe,J. H. Kramer,Bruce R Reed,David Norman,Helena C. Chui,M. W. Weiner,M. W. Weiner +13 more
TL;DR: Using ERC and hippocampus together improved discrimination between AD and CN but did not improve discrimination between MCI and NC; the ERC was better than the hippocampus for distinguishing MCI from AD.
Journal ArticleDOI
Hippocampus and entorhinal cortex in mild cognitive impairment and early AD
Corina Pennanen,Miia Kivipelto,Susanna Tuomainen,Päivi Hartikainen,Tuomo Hänninen,Mikko P. Laakso,Merja Hallikainen,Matti Vanhanen,Aulikki Nissinen,Eeva-Liisa Helkala,Pauli Vainio,Ritva Vanninen,Kaarina Partanen,Hilkka Soininen +13 more
TL;DR: The results suggest that the ERC atrophy precedes hippocampal atrophy in AD, and the E RC volume loss is dominant over the hippocampal volume loss in MCI, whereas more pronounced hippocampalVolume loss appears in mild AD.