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Asla Pitkänen
Researcher at University of Eastern Finland
Publications - 346
Citations - 23445
Asla Pitkänen is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Epilepsy & Epileptogenesis. The author has an hindex of 75, co-authored 332 publications receiving 21492 citations. Previous affiliations of Asla Pitkänen include Oulu University Hospital & Katholieke Universiteit Leuven.
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Organization of intra-amygdaloid circuitries in the rat: An emerging framework for understanding functions of the amygdala
TL;DR: These findings suggest that after the stimulus enters the amygdala, the highly organized intra-amygdaloid circuitries provide a pathway by which the representation of a stimulus becomes distributed in parallel to various amygdaloids nuclei.
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Reciprocal Connections between the Amygdala and the Hippocampal Formation, Perirhinal Cortex, and Postrhinal Cortex in Rat: A Review
TL;DR: The heaviest projections from the amygdala to the hippocampal formation and the parahippocampal areas originate in the lateral, basal, accessory basal, and posterior cortical nuclei, and the underlying principles of organization of these projections are discussed.
Journal Article
MR volumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices.
Ricardo Insausti,K Juottonen,Hilkka Soininen,A. M. Insausti,Kaarina Partanen,Pauli Vainio,Mikko P. Laakso,Asla Pitkänen +7 more
TL;DR: The method provides a tool by which to measure volumes of the entorhinal, perirhinal and temporopolar cortices on coronal MR images and there were no differences between men and women in the volumes of any of the three cortices.
Journal ArticleDOI
Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy
Asla Pitkänen,Thomas P. Sutula +1 more
TL;DR: Therapeutic modification of seizure-induced molecular and cellular responses offers new opportunities for intervention beyond seizure suppression.
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Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy
Rimante Minkeviciene,Sylvain Rheims,Marton B. Dobszay,Misha Zilberter,Jarmo Hartikainen,Lívia Fülöp,Botond Penke,Yuri Zilberter,Yuri Zilberter,Tibor Harkany,Tibor Harkany,Asla Pitkänen,Heikki Tanila +12 more
TL;DR: Overall, these data identify fibrillar Aβ as a pathogenic entity powerfully altering neuronal membrane properties such that hyperexcitability of pyramidal cells culminates in epileptiform activity.