M
Min-Hsiung Pan
Researcher at National Taiwan University
Publications - 336
Citations - 18908
Min-Hsiung Pan is an academic researcher from National Taiwan University. The author has contributed to research in topics: Apoptosis & Cancer. The author has an hindex of 64, co-authored 311 publications receiving 16270 citations. Previous affiliations of Min-Hsiung Pan include China Medical University (Taiwan) & University of Hong Kong.
Papers
More filters
Journal Article
Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.
Ann-Lii Cheng,Hsu Ch,Lin Jk,Hsu Mm,Yunn-Fang Ho,Shen Ts,Ko Jy,Lin Jt,Bor-Ru Lin,Ming-Shiang W,Yu Hs,Shiou-Hwa Jee,Chen Gs,Chen Tm,Chi-An Chen,Lai Mk,Yeong-Shiau Pu,Min-Hsiung Pan,Wang Yj,Tsai Cc,Hsieh Cy +20 more
TL;DR: It is demonstrated that curcumin is not toxic to humans up to 8,000 mg/day when taken by mouth for 3 months and a biologic effect ofCurcumin in the chemoprevention of cancer is suggested.
Journal ArticleDOI
Stability of curcumin in buffer solutions and characterization of its degradation products
Ying-Jan Wang,Min-Hsiung Pan,Ann-Lii Cheng,Liang-In Lin,Yuan Soon Ho,Chang-Yao Hsieh,Jen-Kun Lin +6 more
TL;DR: It was shown that decomposition was pH-dependent and occurred faster at neutral-basic conditions and vanillin, ferulic acid, feruloyl methane were identified as minor degradation products and the amount of vanillin increased with incubation time.
Journal Article
Biotransformation of curcumin through reduction and glucuronidation in mice.
TL;DR: The results, together with previous findings, suggest that curcumin-glucuronoside, dihydrocurcumin - glucuronOSide, THC-gloucesteride, and THC are major metabolites ofCurcumin in vivo.
Journal ArticleDOI
Anti-inflammatory activity of natural dietary flavonoids
TL;DR: Current knowledge and underlying mechanisms on anti-inflammatory activities of flavonoids and their implicated effects in the development of various chronic inflammatory diseases are summarized.
Journal ArticleDOI
Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IκB kinase and NFκB activation in macrophages
TL;DR: Results suggest that curcumin may exert its anti-inflammatory and anti-carcinogenic properties by suppressing the activation of NFkappaB through inhibition of IKK activity.