M
Min Sun
Researcher at University of Oxford
Publications - 3
Citations - 335
Min Sun is an academic researcher from University of Oxford. The author has contributed to research in topics: Excitatory postsynaptic potential & AMPA receptor. The author has an hindex of 3, co-authored 3 publications receiving 246 citations. Previous affiliations of Min Sun include University College London.
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Journal ArticleDOI
Seizure control by decanoic acid through direct AMPA receptor inhibition
Pishan Chang,Katrin Augustin,Kim Boddum,Sophie Williams,Min Sun,John A. Terschak,Jörg D. Hardege,Philip E. Chen,Matthew C. Walker,Robin S.B. Williams +9 more
TL;DR: It is shown that decanoic acid, rather than ketones, provides anti-seizure activity in several ex vivo rat models of epilepsy, likely through the direct inhibition of AMPA receptors.
Journal ArticleDOI
Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin
James Smythies,Min Sun,Norma Masson,Rafik Salama,Peter Simpson,Elizabeth Murray,Viviana K. Neumann,Matthew E. Cockman,Hani Choudhry,Peter J. Ratcliffe,Peter J. Ratcliffe,David R. Mole +11 more
TL;DR: The findings imply that each HIF isoform has an inherent property that determines its binding distribution across the genome, which might be exploited to therapeutically target the specific transcriptional output of each isoform independently.
Journal ArticleDOI
Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer.
Rafik Salama,Norma Masson,Peter Simpson,Lina Katrin Sciesielski,Min Sun,Ya-Min Tian,Peter J. Ratcliffe,David R. Mole +7 more
TL;DR: Different pan-genomic organization of canonical and non-canonical HIF isoform-specific DNA binding at thousands of sites is revealed, suggesting that activation of each HIF-α isoform contributes a highly complex mix of pro- and anti-tumorigenic effects.