Min Zhai

TL;DR: It is proposed that Mn(II) accumulation facilitates recovery from radiation injury and exhibits a concentration-dependent response to manganous chloride [Mn(II).

TL;DR: It is presented the case that protein, rather than DNA, is the principal target of the biological action of IR in sensitive bacteria, and extreme resistance in Mn-accumulating bacteria is based on protein protection.

TL;DR: Microarray data suggest that DEIRA cells efficiently coordinate their recovery by a complex network, within which both DNA repair and metabolic functions play critical roles, including a predicted distinct ATP-dependent DNA ligase and metabolic pathway switching that could prevent additional genomic damage elicited by metabolism-induced free radicals.

TL;DR: A radiation resistant bacterium for the treatment of mixed radioactive wastes containing ionic mercury, and it is demonstrated that different gene clusters could be used to engineer D. radiodurans engineering efforts aimed at integrating several remediation functions into a single host.

TL;DR: The hypothesis that Deinococcus radiodurans and other radiation resistant bacteria accumulate exceptionally high intracellular manganese and low iron levels is extended to include consideration of respiration, tricarboxylic acid cycle activity, peptide transport and metal reduction, which together with Mn(II) transport represent potential new targets to control recovery from radiation injury.