V
Vera Y. Matrosova
Researcher at Uniformed Services University of the Health Sciences
Publications - 29
Citations - 4038
Vera Y. Matrosova is an academic researcher from Uniformed Services University of the Health Sciences. The author has contributed to research in topics: Deinococcus radiodurans & Deinococcus. The author has an hindex of 19, co-authored 26 publications receiving 3648 citations. Previous affiliations of Vera Y. Matrosova include Russian Academy & La Jolla Institute for Allergy and Immunology.
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Journal ArticleDOI
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome.
Michael L. Nickerson,Michelle B. Warren,Jorge R. Toro,Vera Y. Matrosova,Gladys Glenn,Maria L. Turner,Paul H. Duray,Maria J. Merino,Peter L. Choyke,Christian P. Pavlovich,Nirmala Sharma,McClellan M. Walther,David J. Munroe,Robert Hill,Eamonn R. Maher,Cheryl R. Greenberg,Michael I. Lerman,W. Marston Linehan,Berton Zbar,Laura S. Schmidt +19 more
TL;DR: Discovery of disease-causing mutations in BHD, a novel kidney cancer gene associated with renal oncocytoma or chromophobe renal cancer, will contribute to understanding the role of folliculin in pathways common to skin, lung, and kidney development.
Journal ArticleDOI
Accumulation of Mn(II) in Deinococcus radiodurans facilitates gamma-radiation resistance.
Michael J. Daly,Elena K. Gaidamakova,Vera Y. Matrosova,Alexander Vasilenko,Min Zhai,Amudhan Venkateswaran,Matthias Hess,M. V. Omelchenko,Heather M. Kostandarithes,Kira S. Makarova,Lawrence P. Wackett,James K. Fredrickson,Debabrota Ghosal +12 more
TL;DR: It is proposed that Mn(II) accumulation facilitates recovery from radiation injury and exhibits a concentration-dependent response to manganous chloride [Mn(II).
Journal ArticleDOI
Protein Oxidation Implicated as the Primary Determinant of Bacterial Radioresistance
Michael J. Daly,Elena K. Gaidamakova,Vera Y. Matrosova,Alexander Vasilenko,Min Zhai,Richard D. Leapman,Barry Lai,Bruce Ravel,S. W. Li,Kenneth M. Kemner,James K. Fredrickson +10 more
TL;DR: It is presented the case that protein, rather than DNA, is the principal target of the biological action of IR in sensitive bacteria, and extreme resistance in Mn-accumulating bacteria is based on protein protection.
Journal ArticleDOI
Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2.
Laura S. Schmidt,Michelle B. Warren,Michael L. Nickerson,Gregor Weirich,Vera Y. Matrosova,Jorge R. Toro,Maria L. Turner,Paul H. Duray,Maria J. Merino,Stephen M. Hewitt,Christian P. Pavlovich,Gladys Glenn,Cheryl R. Greenberg,W. Marston Linehan,Berton Zbar +14 more
TL;DR: Identification of the gene for BHD may reveal a new genetic locus responsible for renal neoplasia and for lung and hair-follicle developmental defects and is associated with a number of diseases.
Journal ArticleDOI
Small-Molecule Antioxidant Proteome-Shields in Deinococcus radiodurans
Michael J. Daly,Elena K. Gaidamakova,Vera Y. Matrosova,Juliann G. Kiang,Risaku Fukumoto,Duck-Yeon Lee,Nancy B. Wehr,Gabriela A. Viteri,Barbara S. Berlett,Rodney L. Levine +9 more
TL;DR: By establishing that Mn2+-metabolite complexes of D. radiodurans specifically protect proteins against indirect damage caused by gamma-rays delivered in vast doses, the findings provide the basis for a new approach to radioprotection and insight into how surplus Mn budgets in cells combat reactive oxygen species.