M
Mina Yaar
Researcher at Boston University
Publications - 123
Citations - 8766
Mina Yaar is an academic researcher from Boston University. The author has contributed to research in topics: Keratinocyte & Melanocyte. The author has an hindex of 49, co-authored 123 publications receiving 8353 citations. Previous affiliations of Mina Yaar include United States Department of Agriculture & Tufts University.
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Journal ArticleDOI
The pathogenesis of melanoma induced by ultraviolet radiation
TL;DR: Skin cancers, predominantly basal-cell and squamous-cell carcinomas, have accounted for an estimated 40 percent of all cancers in the United States in recent years, and their frequency has been increasing.
Journal ArticleDOI
Photoageing: mechanism, prevention and therapy.
Mina Yaar,Barbara A. Gilchrest +1 more
TL;DR: Improved understanding of the skin’s innate UV protective mechanisms has also given rise to several novel treatment concepts that promise to revolutionize this field within the coming decade.
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Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.
Mina Yaar,S Zhai,Paul F. Pilch,Sineaid M. Doyle,Patricia B. Eisenhauer,Richard E. Fine,Barbara A. Gilchrest +6 more
TL;DR: Using rat cortical neurons and NIH-3T3 cell line engineered to stably express p75NTR, it is found that the beta-amyloid peptide specifically binds the p75 NTR, implying that neuronal death in Alzheimer's disease is mediated, at least in part, by the interaction of beta- amyloid with p 75NTR.
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Mechanisms of ultraviolet light-induced pigmentation.
TL;DR: Overall, ultraviolet-induced melanogenesis may be one part of a eukaryotic SOS response to damaging ultraviolet irradiation that has evolved over time to provide a protective tan in skin at risk of further injury from sun exposure.
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Cellular mechanisms regulating human melanogenesis
TL;DR: The major differentiated function of melanocytes is the synthesis of melanin, a pigmented heteropolymer that is synthesized in specialized cellular organelles termed melanosomes, which are arranged in a supranuclear cap, protecting the DNA against incident ultraviolet light (UV) irradiation.