M
Minna Mäki
Researcher at University of Helsinki
Publications - 29
Citations - 962
Minna Mäki is an academic researcher from University of Helsinki. The author has contributed to research in topics: Multiplex & DNA extraction. The author has an hindex of 16, co-authored 29 publications receiving 895 citations. Previous affiliations of Minna Mäki include Helsinki University Central Hospital.
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Journal ArticleDOI
Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study
Päivi Tissari,Alimuddin Zumla,Eveliina Tarkka,Sointu Mero,Laura E. Savolainen,Martti Vaara,Anne Aittakorpi,Sanna Laakso,Merja Lindfors,Heli Piiparinen,Minna Mäki,C Carder,Jim F. Huggett,Vanya Gant +13 more
TL;DR: Definitive identification of bacterial species with this microarray platform was highly sensitive, specific, and faster than was the gold-standard culture-based method.
Journal ArticleDOI
Analysis of nucleotide sugars from cell lysates by ion-pair solid-phase extraction and reversed-phase high-performance liquid chromatography.
Jarkko Räbinä,Minna Mäki,Emma M. Savilahti,Nina Järvinen,Leena Penttilä,Risto Renkonen,Risto Renkonen +6 more
TL;DR: Practical methods for both extraction of nucleotide sugars from cell lysates and for their analytical separation enable good separation of structurally similar sugar nucleotides, compatibility with rapid evaporative concentration, and possibility to automation.
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Rapid identification of bacterial pathogens using a PCR- and microarray-based assay
Anna-Kaarina Järvinen,Sanna Laakso,Pasi Piiparinen,Anne Aittakorpi,Merja Lindfors,Laura Huopaniemi,Heli Piiparinen,Minna Mäki +7 more
TL;DR: A method based on a modified broad-range PCR and an oligonucleotide microarray for the simultaneous detection and identification of 12 bacterial pathogens at the species level rapidly provides reliable data, which can guide optimal antimicrobial treatment decisions in a timely manner.
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Biosynthesis of 6-deoxyhexose glycans in bacteria.
Minna Mäki,Risto Renkonen +1 more
TL;DR: 6-deoxyhexose biosynthesis of cell surface glycans of three Gram-negative pathogens, Helicobacter pylori, Pseudomonas aeruginosa, and Actinobacillus actinomycetemcomitans serotype a are reviewed.
Journal ArticleDOI
Disposable roll-to-roll hot embossed electrophoresis chip for detection of antibiotic resistance gene mecA in bacteria.
Ralph Liedert,Lotta K. Amundsen,Ari Hokkanen,Minna Mäki,Anne Aittakorpi,Mikko Pakanen,James R. Scherer,Richard A. Mathies,Marika Kurkinen,Sanna Uusitalo,Leena Hakalahti,Tarja K. Nevanen,Harri Siitari,Hans Söderlund +13 more
TL;DR: A high-throughput roll-to-roll (R2R) manufacturing process for foil-based polymethyl methacrylate (PMMA) chips of excellent optical quality and disposable, R2R hot embossed microfluidic chips used for the identification of the antibiotic resistance gene mecA in Staphylococcus epidermidis are presented.