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Miriam A. Friedlander

Researcher at Case Western Reserve University

Publications -  26
Citations -  3662

Miriam A. Friedlander is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Peritoneal dialysis & Pentosidine. The author has an hindex of 19, co-authored 26 publications receiving 3428 citations. Previous affiliations of Miriam A. Friedlander include University Hospitals of Cleveland & French Institute of Health and Medical Research.

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Advanced oxidation protein products as a novel marker of oxidative stress in uremia

Véronique Witko-Sarsat, +14 more
- 01 May 1996 - 
TL;DR: The measurement of AOPP is proposed as a reliable marker to estimate the degree of oxidant-mediated protein damage in uremic patients and to predict the potential efficacy of therapeutic strategies aimed at reducing such an oxidative stress.
Journal Article

Advanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure.

Véronique Witko-Sarsat, +9 more
- 01 Sep 1998 - 
TL;DR: It is demonstrated that AOPP act as a mediator of oxidative stress and monocyte respiratory burst, which points to monocytes as both target and actor in the immune dysregulation associated with chronic uremia.
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Involvement of hydrogen peroxide in collagen cross-linking by high glucose in vitro and in vivo

Abdelhamid Elgawish, +3 more
- 31 May 1996 - 
TL;DR: The role of oxidative stress in protein cross-linking by the Maillard reaction in vitro is confirmed and the first evidence for a role of H2O2 in cross- linking in diabetes is provided.
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Early and advanced glycosylation end products : kinetics of formation and clearance in peritoneal dialysis

Miriam A. Friedlander, +3 more
- 01 Feb 1996 - 
TL;DR: Clearance of protein-associated pentosidine by the peritoneal membrane may explain lower steady state levels in patients treated by PD, yet plasma levels of the AGEpentosidine are significantly lower in PD than in hemodialysis.
Journal ArticleDOI

Influence of dialysis modality on plasma and tissue concentrations of pentosidine in patients with end-stage renal disease

Miriam A. Friedlander, +4 more
- 01 Mar 1995 - 
TL;DR: The results demonstrate that dialysis modality influences the plasma and tissue distribution of pentosidine, and compared with hemodialysis, peritoneal dialysis is associated with lower levels of this glycation end-product in plasma, but with higher levels in the peritoneum.