Miriam E. Martin

TL;DR: The differentiation of heterocysts (steady state, N(2) grown), akinetes, and hormogonia appears to involve the up-regulation of genes distinct for each state, consistent with entry into a nongrowth state.

TL;DR: While different gastric species may show competitive exclusion in the gastric niche, the rhesus gastric microbial community is largely stable despite immune and physiological changes due to H. pylori infection, according to deep sequencing of the bacterial 16S rRNA gene.

TL;DR: Analysis of H pylori strains from mice and from a chronically infected patient showed that CagY functions as an immune-sensitive regulator of T4SS function, proposing that this is a bacterial adaptation to maximize persistent infection and transmission to a new host under conditions of a robust inflammatory response.

TL;DR: It is shown that H. suis in pigs possibly originates from non-human primates, and the data suggest that a host jump from macaques to pigs happened between 100’000 and 15 000 years ago and that pig domestication has had a significant impact on the spread of H.suis in the pig population.

TL;DR: Interactions between H. pylori and bacteria at non-gastric sites are likely indirect—via programming of the pro-inflammatory vs. regulatory T lymphocytes—which may have a significant impact on human health.