M
Mitzi Nagarkatti
Researcher at University of South Carolina
Publications - 363
Citations - 14950
Mitzi Nagarkatti is an academic researcher from University of South Carolina. The author has contributed to research in topics: Immune system & Inflammation. The author has an hindex of 59, co-authored 332 publications receiving 12105 citations. Previous affiliations of Mitzi Nagarkatti include Veterans Health Administration & Virginia Tech.
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Journal Article
Role of cytokines as a double-edged sword in sepsis.
Hina Chaudhry,Juhua Zhou,Juhua Zhou,Yin Zhong,Mir Mustafa Ali,Franklin R. McGuire,Prakash S. Nagarkatti,Mitzi Nagarkatti +7 more
TL;DR: A decrease in IL-6 was associated with a better prognosis and overproduction of IL-10 was found to be the main predictor of severity and fatal outcome, indicating pro-inflammatory and anti-inflammatory cytokines constitute a double-edged sword in sepsis.
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Cannabinoids as novel anti-inflammatory drugs
Prakash S. Nagarkatti,Rupal Pandey,Sadiye Amcaoglu Rieder,Venkatesh L. Hegde,Mitzi Nagarkatti +4 more
TL;DR: This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components.
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Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
Robert J. McKallip,Catherine Lombard,Michael T. Fisher,Billy R. Martin,Seonho Ryu,Steven Grant,Prakash S. Nagarkatti,Mitzi Nagarkatti +7 more
TL;DR: The current data demonstrate that CB2 cannabinoid receptors expressed on malignancies of the immune system may serve as potential targets for the induction of apoptosis, and because CB2 agonists lack psychotropic effects, they may Serve as novel anticancer agents to selectively target and kill tumors of immune origin.
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Activation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitis.
Narendra P. Singh,Udai P. Singh,Balwan Singh,Robert L. Price,Mitzi Nagarkatti,Prakash S. Nagarkatti +5 more
TL;DR: These studies demonstrate for the first time that AhR activation promotes epigenetic regulation thereby influencing reciprocal differentiation of Tregs and Th17 cells, and amelioration of inflammation.
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Macromolecular-clustered facial amphiphilic antimicrobials.
Anisur Rahman,Marpe Bam,Edgar Luat,Moumita Sharmin Jui,Mitra S. Ganewatta,Tinom Shokfai,Mitzi Nagarkatti,Alan W. Decho,Chuanbing Tang +8 more
TL;DR: It is shown that cholic acid derivatives with three charged head groups are more potent and selective than lithocholic and deoxycholic counterparts, particularly against Gram-negative bacteria.