M
Moataz A. Shaldam
Researcher at Kafrelsheikh University
Publications - 34
Citations - 411
Moataz A. Shaldam is an academic researcher from Kafrelsheikh University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 5, co-authored 18 publications receiving 74 citations. Previous affiliations of Moataz A. Shaldam include Tanta University & Delta University for Science and Technology.
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Journal ArticleDOI
In silico screening of potent bioactive compounds from honeybee products against COVID-19 target enzymes.
Moataz A. Shaldam,Galal Yahya,Galal Yahya,Nashwa H Mohamed,Mohamed M. Abdel-Daim,Mohamed M. Abdel-Daim,Yahya Al Naggar,Yahya Al Naggar +7 more
TL;DR: By molecular docking, the profound binding affinity of 14 selected phenolics and terpenes present in honey and propolis (bees glue) are revealed against the main protease (Msuppro/sup) and RNA dependent RNA polymerase (RdRp) enzymes of the novel 2019-nCoV coronavirus
Posted ContentDOI
In Silico Screening of Potent Bioactive Compounds from Honey Bee Products Against COVID-19 Target Enzymes
TL;DR: It is revealed by molecular docking the profound binding affinity of 14 selected phenolics and terpenes present in honey and propolis against the main protease (Mpro) and RNA dependent RNA polymerase (RdRp) enzymes of the novel 2019-nCoV coronavirus.
Journal ArticleDOI
Drugs with new lease of life as quorum sensing inhibitors: for combating MDR Acinetobacter baumannii infections.
TL;DR: Four FDA-approved drugs, besides azithromycin as positive QSI, were tested for potential QS inhibition against clinical A. baumannii isolates and P. aeruginosa standard strain and revealed the potential inhibition of QS by tested drugs.
Journal ArticleDOI
Xylitol Inhibits Growth and Blocks Virulence in Serratia marcescens.
Ahdab N. Khayyat,Wael A H Hegazy,Moataz A. Shaldam,Rasha A Mosbah,Rasha A Mosbah,Ahmad J. Almalki,Tarek S. Ibrahim,Tarek S. Ibrahim,Maan T. Khayat,El-Sayed Khafagy,El-Sayed Khafagy,Wafaa E. Soliman,Wafaa E. Soliman,Hisham A. Abbas +13 more
TL;DR: In this article, the authors explored the antimicrobial and antivirulence activities of xylitol against S. marcescens wound and burn infections and found that xylolitol is a growth and virulence inhibitor.
Journal ArticleDOI
Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors.
Moataz A. Shaldam,Wagdy M. Eldehna,Alessio Nocentini,Zainab M. Elsayed,Tamer M. Ibrahim,Rofaida Salem,Ramadan A. El-Domany,Clemente Capasso,Hatem A. Abdel-Aziz,Claudiu T. Supuran +9 more
TL;DR: In this article, the authors describe the design of different series of benzofuran-based derivatives as potential carbonic anhydrase inhibitors (CAIs) based on bioisosteric replacement for the p-fluorophenyl SLC-0111 tail with the lipophilic 2-methylbenzofuran or 5-bromobenzofuran tails to furnish the 2.