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Mohammad K. Khan

Researcher at Emory University

Publications -  112
Citations -  2657

Mohammad K. Khan is an academic researcher from Emory University. The author has contributed to research in topics: Radiation therapy & Melanoma. The author has an hindex of 26, co-authored 109 publications receiving 2027 citations. Previous affiliations of Mohammad K. Khan include Cleveland Clinic & MetroHealth.

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Does competitive flow reduce internal thoracic artery graft patency

TL;DR: As preoperative proximal coronary stenosis decreased, ITA patency declined; however, at no degree of stenosis was there a sharp decline, and the nature of this relationship indicates ITAs should not be abandoned at moderate grades of stenotic.
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Ipilimumab and Stereotactic Radiosurgery Versus Stereotactic Radiosurgery Alone for Newly Diagnosed Melanoma Brain Metastases.

TL;DR: Use of ipilimumab within 4 months of SRS seems to be safe, with no increase in radiation necrosis or hemorrhage; however, the retrospective institutional experience with this treatment regimen was not associated with improved outcomes.
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Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation.

TL;DR: The known mechanistic data behind the immunostimulatory effects of radiation and how this is enhanced by immunotherapy are summarized and placed in a larger context of understanding T-cell exhaustion and the impact of immunotherapy on this phenotype.
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Exosomes, Their Biogenesis and Role in Inter-Cellular Communication, Tumor Microenvironment and Cancer Immunotherapy.

TL;DR: The exosome biogenesis, their role in inter-cellular communication, and their capacity to modulate the immune system as a part of future cancer immunotherapeutic approaches are discussed and their potential to serve as biomarkers of therapy response is discussed.
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BRAF inhibitor and stereotactic radiosurgery is associated with an increased risk of radiation necrosis.

TL;DR: Multivariable analysis showed that BRAFi predicted an increased risk of both radiographic and SRN compared with SRS alone, and approaches to mitigate RN for patients receiving SRS and BRAFi should be considered until the clinical trial evaluating this treatment regimen is completed.