System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a the brain, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy. Further, the invention enables the incorporation of both sensing and therapeutic devices on the same substrate allowing for faster treatment of diseased tissue and fewer devices to perform the same procedure.

Systems,methods, and devices having stretchable integrated circuitry for sensing and delivering therapy

System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a nerve bundle, or the surface of the heart Such direct, conformal contact increases accuracy of measurement and delivery of therapy

Systems, methods, and devices using stretchable or flexible electronics for medical applications

Digital Hardware Evolution.- An Online EHW Pattern Recognition System Applied to Sonar Spectrum Classification.- Design of Electronic Circuits Using a Divide-and-Conquer Approach.- Implementing Multi-VRC Cores to Evolve Combinational Logic Circuits in Parallel.- An Intrinsic Evolvable Hardware Based on Multiplexer Module Array.- Estimating Array Connectivity and Applying Multi-output Node Structure in Evolutionary Design of Digital Circuits.- Research on the Online Evaluation Approach for the Digital Evolvable Hardware.- Research on Multi-objective On-Line Evolution Technology of Digital Circuit Based on FPGA Model.- Evolutionary Design of Generic Combinational Multipliers Using Development.- Analog Hardware Evolution.- Automatic Synthesis of Practical Passive Filters Using Clonal Selection Principle-Based Gene Expression Programming.- Research on Fault-Tolerance of Analog Circuits Based on Evolvable Hardware.- Analog Circuit Evolution Based on FPTA-2.- Bio-inspired Systems.- Knowledge Network Management System with Medicine Self Repairing Strategy.- Design of a Cell in Embryonic Systems with Improved Efficiency and Fault-Tolerance.- Design on Operator-Based Reconfigurable Hardware Architecture and Cell Circuit.- Bio-inspired Systems with Self-developing Mechanisms.- Development of a Tiny Computer-Assisted Wireless EEG Biofeedback System.- Steps Forward to Evolve Bio-inspired Embryonic Cell-Based Electronic Systems.- Evolution of Polymorphic Self-checking Circuits.- Mechanical Hardware Evolution.- Sliding Algorithm for Reconfigurable Arrays of Processors.- System-Level Modeling and Multi-objective Evolutionary Design of Pipelined FFT Processors for Wireless OFDM Receivers.- Reducing the Area on a Chip Using a Bank of Evolved Filters.- Evolutionary Design.- Walsh Function Systems: The Bisectional Evolutional Generation Pattern.- Extrinsic Evolvable Hardware on the RISA Architecture.- Evolving and Analysing "Useful" Redundant Logic.- Adaptive Transmission Technique in Underwater Acoustic Wireless Communication.- Autonomous Robot Path Planning Based on Swarm Intelligence and Stream Functions.- Research on Adaptive System of the BTT-45 Air-to-Air Missile Based on Multilevel Hierarchical Intelligent Controller.- The Design of an Evolvable On-Board Computer.- Evolutionary Algorithms in Hardware Design.- Extending Artificial Development: Exploiting Environmental Information for the Achievement of Phenotypic Plasticity.- UDT-Based Multi-objective Evolutionary Design of Passive Power Filters of a Hybrid Power Filter System.- Designing Electronic Circuits by Means of Gene Expression Programming II.- Designing Polymorphic Circuits with Evolutionary Algorithm Based on Weighted Sum Method.- Robust and Efficient Multi-objective Automatic Adjustment for Optical Axes in Laser Systems Using Stochastic Binary Search Algorithm.- Minimization of the Redundant Sensor Nodes in Dense Wireless Sensor Networks.- Evolving in Extended Hamming Distance Space: Hierarchical Mutation Strategy and Local Learning Principle for EHW.- Hardware Implementation of Evolutionary Algorithms.- Adaptive and Evolvable Analog Electronics for Space Applications.- Improving Flexibility in On-Line Evolvable Systems by Reconfigurable Computing.- Evolutionary Design of Resilient Substitution Boxes: From Coding to Hardware Implementation.- A Sophisticated Architecture for Evolutionary Multiobjective Optimization Utilizing High Performance DSP.- FPGA-Based Genetic Algorithm Kernel Design.- Using Systolic Technique to Accelerate an EHW Engine for Lossless Image Compression.

Evolvable systems : from biology to hardware : 7th International Conference, ICES 2007, Wuhan, China, September 21-23, 2007 : proceedings

A system and method for an improved biological interface system that processes multicellular signals of a patient and controls one or more devices is disclosed. The system includes a sensor that detects the multicellular signals and a processing unit for producing the control signal based on the multicellular signals. The system may include improved communication, self-diagnostics, and surgical insertion tools.

Biological interface system

The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package, that is suitable for implantation in living tissue, such as for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.

Biocompatible bonding method and electronics package suitable for implantation

A neural prosthetic micro system (100) includes an electrode array (115) coupled to an integrated circuit (IC) (110) which IC may include signal conditioning and processing circuitry. The IC may include a high pass filter that passes signals representative of local field potential (LFP) activity in a subject's brain.

Neural prosthetic micro system

A new SOI device, the MOS-JFET, has been developed that combines two different transistors, JFET and MOSFET, superimposed in a single silicon island so that they share the same body. A unique attribute of the MOS-JFET is that it can be viewed as a four gate transistor (two side junction-based gates, the top MOS gate, and the back gate activated by SOI substrate biasing). Each of these four gates can control the conduction characteristics of the transistor. This novel transistor's multiple gate inputs give rise to exciting circuit opportunities for analog, RF, mixed-signal, and digital applications. Measured results of MOS-JFET transistors, fabricated in a conventional partially-depleted SOI technology, demonstrate that the device is fully operational. From the experiments and systematic 2-D simulations, typical regions of operation are identified. These results indicate that optimum performance is reached when the MOS and junction field-effects are combined.

The multiple-gate mos-jfet transistor

In one embodiment, an electronic device comprises a plurality of electrical switches and a plurality of energy storage elements arrayed relative to one another such that the energy storage elements may be connected in series, or in parallel, or both, to an input and an output.

Switch array and power management system for batteries and other energy storage elements

Battery switch array system with application for JPL's rechargeable micro-scale batteries

A micro-colloid thruster system may be fabricated using micro electromechanical system (MEMS) fabrication techniques. A beam of charged droplets may be extracted from an emitter tip in an emitter array by an extractor electrode and accelerated by an accelerator electrode to produce thrust. The micro-colloid thruster system may be used as the main propulsion system for microspacecraft and for precision maneuvers in larger spacecraft.

Mohammad Mojarradi

Papers

Neural prosthetic micro system

The multiple-gate mos-jfet transistor

Switch array and power management system for batteries and other energy storage elements

Battery switch array system with application for JPL's rechargeable micro-scale batteries

Micro-colloid thruster system