M
Monika Gaba
Researcher at Punjab Technical University
Publications - 10
Citations - 707
Monika Gaba is an academic researcher from Punjab Technical University. The author has contributed to research in topics: Benzimidazole & Type 2 diabetes. The author has an hindex of 8, co-authored 10 publications receiving 538 citations.
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Journal ArticleDOI
Benzimidazole: an emerging scaffold for analgesic and anti-inflammatory agents.
TL;DR: In the present review, published reports on benzimidazole scaffold are collated to provide an insight so that its full therapeutic potential can be utilized for the treatment of pain and inflammation.
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Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions
Monika Gaba,Chander Mohan +1 more
TL;DR: This review enlightens the landscape of the discovery and development of imidazoles- and benzimidazole-based drugs with an emphasis on structure activity relationship features (SAR), medicinal chemistry, and their mechanism of action.
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Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents
TL;DR: A series of novel 5-substituted-1-(phenylsulfonyl)-2-methylbenzimidazole derivatives exhibited moderate to good anti-inflammatory and analgesic activity in carrageenan-induced rat paw edema and acetic acid-induced writhing in mice, respectively, with low ulcerogenicity compared with the standard drug indomethacin.
Journal ArticleDOI
Benzimidazole derivatives: search for GI-friendly anti-inflammatory analgesic agents
Monika Gaba,Punam Gaba,Deepika Uppal,Neelima Dhingra,Malkeet Singh Bahia,Om Silakari,Chander Mohan +6 more
TL;DR: In this paper, the synthesis and biological evaluation of N-1-(phenylsulfonyl)-2-methylamino-substituted-1H-benzimidazole derivatives with lower GI toxicity was described.
Journal ArticleDOI
Synthesis, antimicrobial and cytotoxic activity of novel azetidine-2-one derivatives of 1H-benzimidazole
Malleshappa N. Noolvi,Suresh Agrawal,Harun M. Patel,Aravind M. Badiger,Monika Gaba,Azit Zambre +5 more
TL;DR: A series of 1-methyl-N-((substituted-phenylmethylidene)-1H-benzimidazol-2-amines (4a-4g) were prepared via the formation of 1methyl-1-h-benzmanidazolate-2.2-amine (3), which was pre- pared by the cycloaddition of ophenylenediamine (1) with cyanogen bromide in the presence of aqueous base followed by N-methylation with methyl iodide in