Monika Westphal

TL;DR: Analysis of the integration patterns of Ad12 DNA in the four hamster lines investigated reveals that some of the viral DNA molecules are fragmented prior to or during integration, which is compatible with, but does not prove, the notion that at least a portion of theiral DNA sequences, is integrated into repetitive sequences, or else that the integrated viral sequences have been amplified after integration.

TL;DR: The structure and composition of the core of adenovirus type 2 were analyzed by electron microscopy and biochemical techniques after differential degradation of the virion by heat, by pyridine, or by sarcosyl treatment.

TL;DR: The results of the mapping experiments demonstrate that the mRNA's isolated early from productively and abortively infected and from two lines of transformed cells are derived from the same or similar regions of the adenovirus type 12 genome.

TL;DR: A comparison of the polypeptide composition of the incomplete particles with that of the complete virions by electrophoresis on polyacrylamide slab gels demonstrates that both types of particles contain hexons, penton base and fibers in similar relative amounts.

TL;DR: Theadenovirus type12-specific mRNA and thestable nuclear RNA fromproductively infected KB cells, early postinfection, fromabortively infected BHK-21 cells, and from theadenov virus type 12-transformed hamster lines T637 and HA12/7 have been mapped on thegenome of adenovirustype12.