M
Morten Charles
Researcher at Aarhus University
Publications - 46
Citations - 1073
Morten Charles is an academic researcher from Aarhus University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 16, co-authored 43 publications receiving 741 citations. Previous affiliations of Morten Charles include Aarhus University Hospital & Steno Diabetes Center.
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Journal ArticleDOI
Risk Factors for Incident Diabetic Polyneuropathy in a Cohort With Screen-Detected Type 2 Diabetes Followed for 13 Years: ADDITION-Denmark
Signe T Andersen,Daniel R. Witte,Else-Marie Dalsgaard,Henning Andersen,Peter P. Nawroth,Thomas Fleming,Troels Mygind Jensen,Nanna B. Finnerup,Troels S. Jensen,Torsten Lauritzen,Eva L. Feldman,Brian C. Callaghan,Morten Charles +12 more
TL;DR: This study provides further epidemiological evidence for obesity as a risk factor for DPN and identifies low HDL cholesterol levels and higher levels of methylglyoxal, a marker of dicarbonyl stress, as risk factors for the development of DPN.
Journal ArticleDOI
Long-term Risk of Dementia in Persons With Schizophrenia: A Danish Population-Based Cohort Study
Anette Riisgaard Ribe,Thomas Munk Laursen,Morten Charles,Wayne Katon,Morten Fenger-Grøn,Dimitry S. Davydow,Lydia Chwastiak,Joseph M. Cerimele,Mogens Vestergaard +8 more
TL;DR: Individuals with schizophrenia, especially those younger than 65 years, had a markedly increased relative risk of dementia that could not be explained by established dementia risk factors.
Journal ArticleDOI
Prevalence of Neuropathy and Peripheral Arterial Disease and the Impact of Treatment in People With Screen-Detected Type 2 Diabetes: The ADDITION-Denmark study
Morten Charles,Niels Ejskjaer,Daniel R. Witte,Knut Borch-Johnsen,Torsten Lauritzen,Annelli Sandbæk +5 more
TL;DR: In a population with screen-detected type 2 diabetes, it was found that screening followed by IT led to a statistically significant difference in the prevalence of DPN and PAD 6 years after diagnosis, however, treatment levels were high in both groups.
Journal ArticleDOI
The effects of capillary dysfunction on oxygen and glucose extraction in diabetic neuropathy
Leif Østergaard,Nanna B. Finnerup,Astrid Juhl Terkelsen,Astrid Juhl Terkelsen,Rasmus A. Olesen,Kim Ryun Drasbek,Lone Knudsen,Sune Nørhøj Jespersen,Sune Nørhøj Jespersen,Jan Frystyk,Morten Charles,Reimar W. Thomsen,Jens Sandahl Christiansen,Henning Beck-Nielsen,Henning Beck-Nielsen,Troels S. Jensen,Troels S. Jensen,Henning Andersen +17 more
TL;DR: The analysis suggests testable relations between capillary dysfunction, tissue hypoxia, aldose reductase activity, oxidative stress, tissue inflammation and glucose clearance from blood, and the implications in relation to the prevention and management of diabetic complications in type 1 and type 2 diabetes.
Journal ArticleDOI
Risk Factors for the Presence and Progression of Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: ADDITION-Denmark
Signe T Andersen,Daniel R. Witte,Jesper Fleischer,Henning Andersen,Torsten Lauritzen,Marit E. Jørgensen,Troels S. Jensen,Troels S. Jensen,Rodica Pop-Busui,Morten Charles +9 more
TL;DR: Examination of the course of cardiovascular autonomic neuropathy and related cardiometabolic risk factors in patients with type 2 diabetes confirms that hyperglycemia, obesity, and hypertriglyceridemia are negatively related to indices of CAN, although these effects diminish over time.