M
Mousa O. Germoush
Researcher at Al Jouf University
Publications - 44
Citations - 1133
Mousa O. Germoush is an academic researcher from Al Jouf University. The author has contributed to research in topics: Oxidative stress & Medicine. The author has an hindex of 14, co-authored 33 publications receiving 608 citations.
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Journal ArticleDOI
Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity.
TL;DR: The hepatoprotective effects of UMB appear to depend on co-activation of PPARγ and Nrf2, and subsequent suppression of oxidative stress and inflammation.
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Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy.
Osama Yousef Althunibat,Amir M. Al Hroob,Mohammad H. Abukhalil,Mousa O. Germoush,May Bin-Jumah,Ayman M. Mahmoud +5 more
TL;DR: Fisetin attenuated the development of DCM via amelioration of hyperglycemia/hyperlipidemia‐mediated oxidative stress, inflammation and apoptosis in the diabetic heart through suppression of oxidative stress and boosted antioxidant defenses in the heart of diabetic rats.
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Berberine mitigates cyclophosphamide-induced hepatotoxicity by modulating antioxidant status and inflammatory cytokines
TL;DR: Berberine showed a marked hepatoprotective effect against CP-induced hepatotoxicity through alleviation of the elevated serum marker enzymes in addition to its antioxidant and anti-inflammatory efficacies.
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Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats.
Saleem Aladaileh,Omnia E. Hussein,Mohammad H. Abukhalil,Sultan A M Saghir,May Bin-Jumah,Manal A. Alfwuaires,Mousa O. Germoush,Amer A. Almaiman,Ayman M. Mahmoud +8 more
TL;DR: FN prevents MTX-induced AKI by activating Nrf2/HO-1 signaling and attenuates oxidative damage and inflammation and may represent an effective adjuvant that can prevent MTX nephrotoxicity, pending further mechanistic studies.
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The Multifaceted Role of Curcumin in Advanced Nanocurcumin Form in the Treatment and Management of Chronic Disorders
Priti Tagde,Pooja Tagde,Fahadul Islam,Sandeep Tagde,Muddaser Shah,Zareen Delawar Hussain,Md. Habibur Rahman,Agnieszka Najda,Ibtesam S. Alanazi,Mousa O. Germoush,Hanan R. H. Mohamed,Mardi M. Algandaby,Mohammed Z. Nasrullah,Natalia Kot,Mohamed M. Abdel-Daim +14 more
TL;DR: In this paper, the authors highlight the therapeutic benefits of nanocurcumin over curcumin and highlight the potential of encapsulating or loading nanocURcumin to increase its therapeutic potential.