M
Mriganka Sur
Researcher at Picower Institute for Learning and Memory
Publications - 331
Citations - 30456
Mriganka Sur is an academic researcher from Picower Institute for Learning and Memory. The author has contributed to research in topics: Visual cortex & Lateral geniculate nucleus. The author has an hindex of 88, co-authored 323 publications receiving 27646 citations. Previous affiliations of Mriganka Sur include Vanderbilt University & Massachusetts Institute of Technology.
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Journal ArticleDOI
MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling.
Nikolaos Mellios,Nikolaos Mellios,Danielle A. Feldman,Steven D. Sheridan,Steven D. Sheridan,Jacque P.K. Ip,Showming Kwok,Stephen K. Amoah,Bess P. Rosen,Brian A. Rodriguez,Benjamin Crawford,Radha Swaminathan,Stephanie Chou,Yun Li,Mark N. Ziats,Carl Ernst,Rudolf Jaenisch,Stephen J. Haggarty,Mriganka Sur +18 more
TL;DR: A novel miRNA-mediated pathway downstream of MeCP2 that influences neurogenesis via interactions with central molecular hubs linked to autism spectrum disorders is supported.
Journal ArticleDOI
Active control of arousal by a locus coeruleus GABAergic circuit
TL;DR: A local population of GABAergic neurons (LC-GABA) is revealed capable of modulating LC-NA activity and arousal, and how this circuit regulates arousal gain and tone is shown.
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Foci of orientation plasticity in visual cortex.
TL;DR: It is demonstrated that neurons in the cat striate cortex (V1) show pronounced adaptation-induced short-term plasticity of orientation tuning primarily at specific foci, mediated by inhomogeneities in local intracortical interactions that are overlaid on the map of orientation preference.
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An acetylcholine-activated microcircuit drives temporal dynamics of cortical activity
TL;DR: In this article, the authors found that cholinergic inputs to mouse visual cortex specifically and differentially drive a defined cortical microcircuit: they facilitate somatostatin-expressing (SOM) inhibitory neurons that in turn inhibit parvalbuminexpressing inhibitory neuron and pyramidal neurons.
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Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes
Naiyan Chen,Hiroki Sugihara,Jitendra Sharma,Jitendra Sharma,Gertrudis Perea,Jeremy Petravicz,Chuong Le,Mriganka Sur +7 more
TL;DR: A unique and surprising role for astrocytes is revealed in NB-induced stimulus-specific plasticity in the cerebral cortex through cholinergic innervation of the cortex by the nucleus basalis via muscarinic AChRs.