M
Mriganka Sur
Researcher at Picower Institute for Learning and Memory
Publications - 331
Citations - 30456
Mriganka Sur is an academic researcher from Picower Institute for Learning and Memory. The author has contributed to research in topics: Visual cortex & Lateral geniculate nucleus. The author has an hindex of 88, co-authored 323 publications receiving 27646 citations. Previous affiliations of Mriganka Sur include Vanderbilt University & Massachusetts Institute of Technology.
Papers
More filters
Journal ArticleDOI
Development and plasticity of cortical areas and networks.
Mriganka Sur,Catherine A. Leamey +1 more
TL;DR: Surprisingly, the behavioural role of 'rewired' cortex is also influenced profoundly, indicating the importance of patterned activity for this key aspect of cortical function.
Journal ArticleDOI
Invariant computations in local cortical networks with balanced excitation and inhibition
Jorge Mariño,James Schummers,David C. Lyon,David C. Lyon,Lars Schwabe,Oliver Beck,Peter Wiesing,Klaus Obermayer,Mriganka Sur +8 more
TL;DR: A mechanism by which orientation selectivity is computed invariantly in cat primary visual cortex across an orientation preference map that provides a wide diversity of local circuits is demonstrated.
Journal ArticleDOI
Dendritic spine dynamics are regulated by monocular deprivation and extracellular matrix degradation.
TL;DR: It is shown that rapid structural changes at the level of dendritic spines occur following brief monocular deprivation, suggesting that this mechanism is active in vivo to permit structural remodeling during ocular dominance plasticity.
Journal ArticleDOI
Disruption of retinogeniculate afferent segregation by antagonists to NMDA receptors.
TL;DR: It is reported here that blockade of N-methyl-D-aspartate (NMDA) receptors on LGN cells with specific antagonists during the period of sublamina formation prevents retinal afferents from segregating into 'On' and 'Off sublaminee'.
Journal ArticleDOI
Induction of Expansion and Folding in Human Cerebral Organoids
Yun Li,Julien Muffat,Attya Omer,Irene Bosch,Madeline A. Lancaster,Mriganka Sur,Lee Gehrke,Lee Gehrke,Juergen A. Knoblich,Rudolf Jaenisch +9 more
TL;DR: It is shown that increasing NP proliferation induces expansion and folding in an in-vitro model of human corticogenesis, and the expanded cerebral organoids are utilized to show that infection with Zika virus impairs cortical growth and folding.