Showing papers by "Muhammad Kaleem Khosa published in 2021"
TL;DR: The worldwide demand has been raised to use natural dyes in all applied fields of life due to their environmental-friendly and therapeutic nature as discussed by the authors, and microwave rays as an eco-fri...
Abstract: The worldwide demand has been raised to use natural dyes in all applied fields of life due to their environmental-friendly and therapeutic nature. For the current study microwave rays as an eco-fri...
22 citations
TL;DR: In this article, the authors investigated the effectiveness of remdesivir in both diabetic and non-diabetic individuals who were suffering from a severe infection of novel coronavirus disease (COVID-19).
Abstract: We aimed to investigate the interventions of remdesivir in both diabetic and nondiabetic individuals who were suffering from a severe infection of novel coronavirus disease (COVID-19). In this study, we aimed to explore the relationship between therapeutic effectiveness of remdesivir and complications of diabetes mellitus by observing the recovery period among diabetic and nondiabetic patients associated with COVID-19 infection. A total of 850 COVID-19 patients were recruited for this study, out of which 48% were diabetic and 52% were nondiabetics. The results of this study indicated that nondiabetic individuals administered with remdesivir recovered from COVID-19 within 10 days showing a 95% confidence interval (p < 0.01), while the diabetic individuals recovered in 15 days. Nondiabetic patients administered with remdesivir exhibited higher chances of clinical improvement at 15th day than those who were associated with diabetes. Remdesivir administration improved the levels of various biochemical parameters, such as C-reactive protein, lactate dehydrogenase, d-Dimer, and ferritin both in diabetic and nondiabetic patients. However, a significant improvement (p < 0.01) was seen in the level of biochemical parameters among nondiabetic patients as compared to that of diabetic patients administered with remdesivir treatment. In the end, it was concluded that remdesivir could be considered as a possible therapeutic agent in the treatment of COVID-19 both in diabetic and nondiabetic situations. However, diabetic patients showed a delayed recovery as compared with that of nondiabetic patients, in which the recovery rate was high.
6 citations
TL;DR: In this article, the synthesis of PVC/ABS/ZnO nanocomposites with Zinc oxide nanoparticles of particle size less than 50 nm by sonication and solution casting techniques was discussed.
Abstract: The Present study deals with synthesis of PVC/ABS/ZnO nanocomposites with Zinc oxide nanoparticles of particle size less than 50 nm by sonication and solution casting techniques. After characterization, such nanocomposite materials were subjected to thermal study, antibiofilm, antibacterial and antioxidant screening. Nanocomposites films showed higher thermal stability than pure polymer matrix loaded with different ZnO-Nps concentration with homogeneous distribution. Antibacterial studies were carried out against selected gram-positive bacteria: Staphylococcus aureus and gram-negative bacteria: Pseudomonas aeruginosa. Selective antibiofilm activity was studied against Staphylococcus aureus and Pseudomonas aeruginosa, which showed a higher to lower activity as a model pathogenic strains (∼93 and ∼89 at 160 µg/ml concentration, respectively), while free radical scavenging capacity was assessed by DPPH, ABTH·+ and FRAP methods. PVC/ABS/ZnO nanocomposite showed larger zones of inhibition and higher antibiofilm and antioxidant activity than PVC/ABS polymer matrix. PVC/ABS/ZnO nanocomposite showed enhanced thermal stability and biological properties that qualify them for different biomedical and industrial applications.
6 citations
TL;DR: In this paper, a new PVC/ABS and CoCl2 composites with various concentrations of cobalt chloride (≤10 wt. %) were synthesized by solution casting techniques and investigated by spectro-chemical, morphological and thermal mode of characterization.
Abstract: New PVC/ABS and CoCl2 composites with various concentrations of cobalt chloride (≤10 wt. %) were synthesized by solution casting techniques and investigated by spectro-chemical, morphological and thermal mode of characterization. The FT-IR, XRD and SEM analyses proved the smooth distribution and uniformity of the constituents of the composite materials. Thermal behavior showed that the addition of CoCl2 to the PVC/ABS blends enhanced the thermal stability and improved mechanical properties of composites due to crosslinking between PVC/ABS blend and CoCl2. Thus based on their remarkable morphology, thermomechanical stability and promising bioactivities, the synthesized composites could be applied for high performance polymeric materials in the field of biomedics and electronics.
1 citations