M
Munusamy Arumugam
Researcher at University of Madras
Publications - 39
Citations - 1137
Munusamy Arumugam is an academic researcher from University of Madras. The author has contributed to research in topics: Agglutinin & Nitric oxide synthase. The author has an hindex of 18, co-authored 38 publications receiving 1016 citations. Previous affiliations of Munusamy Arumugam include Centers for Disease Control and Prevention.
Papers
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Journal ArticleDOI
Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats.
Srinivasan Kalayarasan,Ponnuraj Nagendra Prabhu,Narayanan Sriram,Ramar Manikandan,Munusamy Arumugam,Ganapasam Sudhandiran +5 more
TL;DR: DAS enhances antioxidants and suppresses inflammatory cytokines through the activation of Nrf2, thereby protecting the cell against oxidative stress induced by gentamicin.
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Activation of prophenoloxidase in the plasma and haemocytes of the marine mussel Perna viridis Linnaeus.
TL;DR: This study demonstrates the selective response of plasma and haemocytic proPO to activation by different types of bacterial LPS tested and suggests that proPO system in both plasma andHaemocytes of P. viridis serves an important function in non-self recognition and host immune reactions.
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Ameliorative effects of curcumin against renal injuries mediated by inducible nitric oxide synthase and nuclear factor kappa B during gentamicin-induced toxicity in Wistar rats.
Ramar Manikandan,M. Beulaja,R. Thiagarajan,Asokan Priyadarsini,Rajendran Saravanan,Munusamy Arumugam +5 more
TL;DR: Curcumin enhances antioxidants, and decreases iNOS and NF-κB, thereby protecting the cells against oxidative stress induced by gentamicin.
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Anti-cataractogenic effect of curcumin and aminoguanidine against selenium-induced oxidative stress in the eye lens of Wistar rat pups: An in vitro study using isolated lens.
Ramar Manikandan,R. Thiagarajan,Sivagnanam Beulaja,S. Chindhu,K. Mariammal,Ganapasam Sudhandiran,Munusamy Arumugam +6 more
TL;DR: Curcumin and AG suppressed selenium-induced oxidative stress and cataract formation in isolated lens from Wistar rat pups, possibly by inhibiting depletion of enzymic as well as non-enzymic antioxidants, and preventing uncontrolled generation of free radicals and also by inhibition of iNOS expression.
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Effect of curcumin on selenite-induced cataractogenesis in Wistar rat pups.
TL;DR: The presence of oxidative stress in selenite cataract development and its prevention byCurcumin support the possibility that the natural consumption of curcumin in food can help prevent the onset of senile cataracts.