M
Muttuswamy Sivakumaran
Researcher at Peterborough City Hospital
Publications - 13
Citations - 191
Muttuswamy Sivakumaran is an academic researcher from Peterborough City Hospital. The author has contributed to research in topics: Promoter & Particle. The author has an hindex of 6, co-authored 13 publications receiving 109 citations.
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Journal ArticleDOI
Characterisation of the protein corona using tunable resistive pulse sensing: determining the change and distribution of a particle’s surface charge
Emma L. C. J. Blundell,Matthew J. Healey,Elizabeth Holton,Muttuswamy Sivakumaran,Sarabjit Manstana,Mark Platt +5 more
TL;DR: The technology presented offers an interesting insight into protein corona structure and kinetics of formation measured in biologically relevant solutions, i.e. high protein, high salt levels, and its particle-by-particle analysis gives a measure of the distribution of particle zeta potential that may offer a better understanding of the behaviour of nanoparticles in solution.
Journal ArticleDOI
Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles.
Yamir Islam,Andrew G. Leach,Andrew G. Leach,Jayden Smith,Stefano Pluchino,Christopher R. Coxon,Christopher R. Coxon,Muttuswamy Sivakumaran,J. E. G. Downing,Amos A. Fatokun,Meritxell Teixidò,Touraj Ehtezazi +11 more
TL;DR: The physiological changes to the diseased brain and aged brain are covered in the context of drug delivery to the brain using nanoparticles as well as novel in vitro BBB models.
Journal ArticleDOI
Peptide based drug delivery systems to the brain
Yamir Islam,Andrew G. Leach,Andrew G. Leach,Jayden Smith,Stefano Pluchino,Christopher R Coxonl,Christopher R Coxonl,Muttuswamy Sivakumaran,J. E. G. Downing,Amos A. Fatokun,Meritxell Teixidò,Touraj Ehtezazi +11 more
TL;DR: In this paper, the authors used camera trapping data and spatially explicit capture-recapture models to estimate density and corresponding population size of jaguars in Emas National Park.
Journal ArticleDOI
Tunable resistive pulse sensing: potential applications in nanomedicine.
TL;DR: The potential of a relative newcomer, tunable resistive pulse sensing, for the characterization of nanomaterials and its applications in nanodiagnostics is discussed.
Journal ArticleDOI
In vitro IFN-α release from IFN-α- and pegylated IFN-α-loaded poly(lactic-co-glycolic acid) and pegylated poly(lactic-co-glycolic acid) nanoparticles
Tivadar Feczkó,Tivadar Feczkó,Tivadar Feczkó,Andrea Fodor-Kardos,Andrea Fodor-Kardos,Muttuswamy Sivakumaran,Quazi T.H. Shubhra +6 more
TL;DR: The PEG-IFN-α in poly(lactic-co-glycolic acid)-polyethylene glycol was the most promising nanoparticle among the four formulations because of its remarkably constant release in both phosphate-buffered saline and plasma.