Mark Platt

TL;DR: This approach reveals a complex sequence-fitness mapping, and hypotheses for the physical basis of aptameric binding, and enables rapid design of novel aptamers with desired binding properties, and demonstrates an extension to the approach by incorporating prior knowledge into CLADE, resulting in some of the tightest binding sequences.

TL;DR: It is demonstrated that the resistive pulse signal of a rod is fundamentally different from that of a sphere, which will facilitate multiplexed detection in agglutination assays, as particles with a particular aspect ratio can be distinguished by two measurements.

TL;DR: It is demonstrated that motility across the kinesin motor surface is retained following magnetic functionalization of the microtubules, while gliding speed is dependent on loading level of the neutravidin linker as well as magnetic nanoparticles.

TL;DR: This work shows that by selectively functionalizing microtubule segments with 20-nm CoFe2O4 magnetic nanoparticles, external magnetic fields can be used to control the transport direction of gliding microtubules without affecting their transport speed.

TL;DR: Tunable resistive pulse sensing (TRPS) is used which utilizes a tunable pore to monitor the translocation times of nanoparticles with DNA modified surfaces and demonstrates the ability to resolve the signals for ssDNA, dsDNA, small changes in base length for nucleotides between 15 and 40 bases long, and even the discrimination between partial and fully complementary target sequences.