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N C Gordon
Researcher at John Radcliffe Hospital
Publications - 3
Citations - 592
N C Gordon is an academic researcher from John Radcliffe Hospital. The author has contributed to research in topics: Drug resistance & Vancomycin. The author has an hindex of 3, co-authored 3 publications receiving 534 citations.
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Journal ArticleDOI
Prediction of Staphylococcus aureus Antimicrobial Resistance by Whole-Genome Sequencing
N C Gordon,James Price,Kevin Cole,Richard G. Everitt,Marcus Morgan,John Finney,Angela Kearns,Bruno Pichon,Bernadette C. Young,Daniel J. Wilson,Martin J. Llewelyn,John Paul,Tim E. A. Peto,Derrick W. Crook,A S Walker,Tanya Golubchik +15 more
TL;DR: WGS was as sensitive and specific as routine antimicrobial susceptibility testing methods and is a promising alternative to culture methods for resistance prediction in S. aureus and ultimately other major bacterial pathogens.
Journal ArticleDOI
A pilot study of rapid benchtop sequencing of Staphylococcus aureus and Clostridium difficile for outbreak detection and surveillance
David W Eyre,Tanya Golubchik,N C Gordon,Rory Bowden,Paolo Piazza,Elizabeth M. Batty,Ip Clc.,Daniel J. Wilson,Xavier Didelot,Lily O’Connor,R Lay,David Buck,Angela Kearns,A Shaw,John E. Paul,Mark H. Wilcox,Peter Donnelly,Peto Tea.,Anne-Sophie Walker,Derrick W. Crook +19 more
TL;DR: This benchtop sequencing technology is widely generalisable to human bacterial pathogens and provides several good examples of how rapid and precise sequencing could transform identification of transmission of healthcare-associated infection and therefore improve hospital infection control and patient outcomes in routine clinical practice.
Journal ArticleDOI
Whole-genome sequencing in hierarchy with pulsed-field gel electrophoresis: the utility of this approach to establish possible sources of MRSA cross-transmission.
Ginny Moore,Ginny Moore,B. Cookson,N C Gordon,R. Jackson,Angela Kearns,J. Singleton,Deborah Smyth,Apr Wilson +8 more
TL;DR: Whole-genome sequencing can complement conventional typing methods by confirming or refuting possible MRSA transmission hypotheses and support links between patients occupying the same bay, the same bed space, adjacent isolation rooms and different wards.