N Doughty

TL;DR: Dysregulation of a broad range of inflammatory mediators in idiopathic and familial PAH demonstrates that cytokine levels have a previously unrecognized impact on patient survival and cytokines may prove to be useful biomarkers and provide insight into the contribution of inflammation in PAH.

TL;DR: The CAMPHOR is a valuable new instrument for assessing patient-reported outcome in PH clinical trials and routine practice and exhibited convergent, divergent and known groups validity.

TL;DR: Although this pilot study was insufficiently powered to test the primary end point, it did suggest beneficial effects in favor of sildenafil in several secondary end points at both 3 months and 12 months.

TL;DR: Pre-operative evaluation with NT-proBNP and 6MWD helps risk-stratify patients prior to PEA and both markers correlate with changes in disease burden and right ventricular function.

TL;DR: Repeated CAMPHOR assessment over time appears not to add predictive value of CD to that obtained at diagnosis, although it still informs physicians of important changes in self-reported symptoms.