J
Joanna Pepke-Zaba
Researcher at Papworth Hospital
Publications - 209
Citations - 15779
Joanna Pepke-Zaba is an academic researcher from Papworth Hospital. The author has contributed to research in topics: Pulmonary hypertension & Pulmonary embolism. The author has an hindex of 53, co-authored 185 publications receiving 12692 citations.
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Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension.
TL;DR: Although SVR fell substantially after prostacyclin in patients with pulmonary hypertension, inhaled NO had no effect on SVR in any patient or volunteer, and seems to be both a selective and effective pulmonary vasodilator.
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Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Results From an International Prospective Registry
Joanna Pepke-Zaba,Marion Delcroix,Irene Lang,Eckhard Mayer,Pavel Jansa,David Ambroz,Carmen M. Treacy,Andrea Maria D'Armini,Marco Morsolini,Repke J. Snijder,Paul Bresser,Adam Torbicki,Bent Bruun Kristensen,Jerzy Lewczuk,Iveta Simkova,Joan Albert Barberà,Marc de Perrot,Marius M. Hoeper,Sean Gaine,Rudolf Speich,Miguel Ángel Gómez-Sánchez,Gabor Kovacs,A. Hamid,Xavier Jaïs,Gérald Simonneau +24 more
TL;DR: Despite similarities in clinical presentation, operable and nonoperable CTEPH patients may have distinct associated medical conditions.
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Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension
Elaine Soon,Alan M. Holmes,Carmen M. Treacy,N Doughty,Laura Southgate,Rajiv D. Machado,Richard C. Trembath,Simon Jennings,Lucy Barker,Paul Nicklin,Christoph Walker,David C. Budd,Joanna Pepke-Zaba,Nicholas W. Morrell +13 more
TL;DR: Dysregulation of a broad range of inflammatory mediators in idiopathic and familial PAH demonstrates that cytokine levels have a previously unrecognized impact on patient survival and cytokines may prove to be useful biomarkers and provide insight into the contribution of inflammation in PAH.
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Connective Tissue Disease-associated Pulmonary Arterial Hypertension in the Modern Treatment Era
Robin Condliffe,David G. Kiely,Andrew J. Peacock,Paul A. Corris,J. Simon R. Gibbs,Florenc Vrapi,Clare Das,Charlie Elliot,Martin Johnson,Julia DeSoyza,Chantal Torpy,Kimberley Goldsmith,Denise Hodgkins,Rodney Hughes,Joanna Pepke-Zaba,J. Gerry Coghlan +15 more
TL;DR: Survival of patients with SSc-PAH in the modern treatment era is better than in historical series, and a significant proportion of patientswith mild functional impairment or exercise-induced pulmonary arterial hypertension have evidence of disease progression.
Journal ArticleDOI
Surgical management and outcome of patients with chronic thromboembolic pulmonary hypertension: Results from an international prospective registry
Eckhard Mayer,David P. Jenkins,Jaroslav Lindner,Andrea Maria D'Armini,Jaap J. Kloek,Bart Meyns,Lars B. Ilkjaer,Walter Klepetko,Marion Delcroix,Irene Lang,Joanna Pepke-Zaba,Gérald Simonneau,Philippe Dartevelle +12 more
TL;DR: Pulmonary endarterectomy is associated with a low in-hospital mortality rate and improvements in hemodynamics and exercise capacity and New York Heart Association functional class improved.