N
Nadine Azas
Researcher at Aix-Marseille University
Publications - 52
Citations - 1439
Nadine Azas is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Plasmodium falciparum & Quinoxaline. The author has an hindex of 20, co-authored 52 publications receiving 1187 citations. Previous affiliations of Nadine Azas include University of the Mediterranean & Université Paul Cézanne Aix-Marseille III.
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Journal ArticleDOI
1,3-Diphenylpyrazoles: synthesis and antiparasitic activities of azomethine derivatives
Pascal Rathelot,Nadine Azas,Hussein El-Kashef,F. Delmas,Carole Di Giorgio,P. Timon-David,José Maldonado,Patrice Vanelle +7 more
TL;DR: In the most cases, nitrated compounds were found to be more efficient than non-nitrated ones against Plasmodium falciparum, Trichomonas vaginalis and Leishmania infantum.
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Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines
Pierre Verhaeghe,Nadine Azas,Monique Gasquet,Sébastien Hutter,Christophe Ducros,Michèle Laget,Sylvain Rault,Pascal Rathelot,Patrice Vanelle +8 more
TL;DR: A series of original 4-aryl-substituted 2-trichloromethylquinazoline derivatives was synthesized using a microwave-assisted Suzuki-Miyaura cross-coupling approach, revealing their antiplasmodial potential.
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Original quinazoline derivatives displaying antiplasmodial properties.
Youssef Kabri,Nadine Azas,Aurélien Dumètre,Sébastien Hutter,Michèle Laget,Pierre Verhaeghe,Armand Gellis,Patrice Vanelle +7 more
TL;DR: The structure activity relationships establish that the molecular scaffold which exerts the best profile is the 6-nitro-2-(tosylmethyl)-N-(3-substituted-phenyl)-quinazolin-4-amine, showing that these molecules display a selective antiplasmodial activity.
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Phytochemical and pharmacological study of roots and leaves of Guiera senegalensis J.F. gmel (combretaceae)
Julien Fiot,Souleymane Sanon,Nadine Azas,Valérie Mahiou,Olivia Jansen,Luc Angenot,G. Balansard,Evelyne Ollivier +7 more
TL;DR: The potent synergistic antimalarial interaction between Guiera senegalensis and two plants commonly associated in traditional remedies: Mitragyna inermis and Pavetta crassipes was evaluated and a synergistic effect was shown between total alkaloids extracted from leaves of Guieranone A and those of Mitragynas inerm is.
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Synthesis and antiprotozoal activity of 4-arylcoumarins.
Jean-Thomas Pierson,Jean-Thomas Pierson,Aurélien Dumètre,Sébastien Hutter,F. Delmas,Michèle Laget,Jean-Pierre Finet,Nadine Azas,Sébastien Combes +8 more
TL;DR: A large series of 4-arylcoumarins synthesized by Suzuki-Miyaura cross-coupling reaction and evaluated for antiprotozoal activity against Plasmodium falciparum and Leishmania donovani found to strongly inhibit the proliferation of human cell line and/or parasites.