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Nadine Peart Akindele
Researcher at Johns Hopkins University School of Medicine
Publications - 7
Citations - 87
Nadine Peart Akindele is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications receiving 27 citations.
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Journal ArticleDOI
Acute covid-19 and multisystem inflammatory syndrome in children.
TL;DR: The most common symptoms in children with acute SARS-CoV-2 infection (covid-19 disease) are fever and cough, and other symptoms may include sore throat, rhinorrhoea, or congestion, myalgias, headache, fatigue, and gastrointestinal symptoms including nausea, vomiting, or diarrhoea.
Journal ArticleDOI
Distinct Cytokine and Chemokine Dysregulation in Hospitalized Children With Acute Coronavirus Disease 2019 and Multisystem Inflammatory Syndrome With Similar Levels of Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 Shedding.
Nadine Peart Akindele,Theodore Kouo,Andrew H. Karaba,Oren Gordon,Katherine Z.J. Fenstermacher,Jeanette Beaudry,Jessica H. Rubens,Christine C. Atik,Weiqiang Zhou,Hongkai Ji,Xueting Tao,Dhananjay Vaidya,Heba H. Mostafa,Patrizio Caturegli,Paul W Blair,Lauren Sauer,Andrea L. Cox,Deborah Persaud,Deborah Persaud +18 more
TL;DR: In this paper, a prospective cohort study of children with and without Multisystem Inflammatory Syndrome in Children (MIS-C) confirmed COVID-19 (N=53) was conducted.
Journal ArticleDOI
Continued Virus-Specific Antibody-Secreting Cell Production, Avidity Maturation and B Cell Evolution in Patients Hospitalized with COVID-19.
Maggie L. Bartlett,San Suwanmanee,Nadine Peart Akindele,Shristi Ghimire,Andy K P Chan,Chenxu Guo,Stephen Jay Gould,Andrea L. Cox,Diane E. Griffin +8 more
TL;DR: Cross-sectional and longitudinal analyses of peripheral blood mononuclear cells and plasma collected from 55 hospitalized patients up to 4 months after onset of COVID-19 symptoms indicate ongoing antigen-specific stimulation, maturation, and production of ASCs for several months after appearance and disappearance of virus-specific antibody-secreting cells in circulation.
Journal ArticleDOI
B-Cell Responses in Hospitalized Severe Acute Respiratory Syndrome Coronavirus 2–Infected Children With and Without Multisystem Inflammatory Syndrome
TL;DR: Overall, B-cell responses were similar, but those with MIS-C demonstrated a more mature antibody response at presentation compared to COVID-19, suggesting a postinfectious entity.
Journal ArticleDOI
Effect of remdesivir post-exposure prophylaxis and treatment on pathogenesis of measles in rhesus macaques
Nadine Peart Akindele,J Brockhurst,Shristi Ghimire,San Suwanmanee,Lisa Pieterse,Kelly A. Metcalf Pate,Elaine Bunyan,Roy Bannister,Tomas Cihlar,Danielle P. Porter,Diane E. Griffin +10 more
TL;DR: In this article , the authors evaluated both post-exposure prophylaxis and treatment with remdesivir, a broad-spectrum antiviral, using a well-characterized rhesus macaque model of measles.