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Deborah Persaud
Researcher at Johns Hopkins University School of Medicine
Publications - 106
Citations - 6608
Deborah Persaud is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Viral load & Medicine. The author has an hindex of 35, co-authored 90 publications receiving 5943 citations. Previous affiliations of Deborah Persaud include Johns Hopkins University & University of Massachusetts Medical School.
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Journal ArticleDOI
The challenge of viral reservoirs in HIV-1 infection.
TL;DR: The latent reservoir in resting CD4(+) T cells appears to be sufficient to guarantee lifetime persistence of HIV-1 in the majority of patients on current HAART regimens, and unless new approaches are developed, eradication will not be possible.
Journal ArticleDOI
Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant
Deborah Persaud,Carrie Ziemniak,Ya Hui Chen,Michael Piatak,Tae Wook Chun,Matthew C. Strain,Matthew C. Strain,Douglas D. Richman,Douglas D. Richman,Katherine Luzuriaga +9 more
TL;DR: The case of an infant born to a woman with human immunodeficiency virus type 1 (HIV-1) infection began receiving antiretroviral therapy 30 hours after birth suggests that very early ART in infants may alter the establishment and long-term persistence of HIV-1 infection.
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Residual Human Immunodeficiency Virus Type 1 Viremia in Some Patients on Antiretroviral Therapy Is Dominated by a Small Number of Invariant Clones Rarely Found in Circulating CD4+ T Cells
Justin R. Bailey,Ahmad R. Sedaghat,Tara L. Kieffer,Timothy P. Brennan,Patricia K. Lee,Megan Wind-Rotolo,Christine M. Haggerty,Ashrit R. Kamireddi,Yi Liu,Jessica Lee,Deborah Persaud,Joel E. Gallant,Joseph Cofrancesco,Thomas C. Quinn,Thomas C. Quinn,Claus O. Wilke,Stuart C. Ray,Janet D. Siliciano,Richard E. Nettles,Robert F. Siliciano,Robert F. Siliciano +20 more
TL;DR: In some patients on antiretroviral therapy, the major mechanism for residual viremia involves prolonged production of a small number of viral clones without evident evolution, possibly by cells other than circulating CD4+ T cells.
Journal ArticleDOI
Neurocysticercosis in an orthodox jewish community in New York City
Peter M. Schantz,Anne C. Moore,Jose Munoz,Barry J. Hartman,John A. Schaefer,Alan M. Aron,Deborah Persaud,Elsa Sarti,Marianna Wilson,Ana Flisser +9 more
TL;DR: A diagnosis of neurocysticercosis should be considered in patients with seizures and radiologic evidence of cystic brain lesions, even in those who do not eat pork and who have not traveled to a country in which T. solium infection is endemic.
Journal ArticleDOI
International AIDS Society global scientific strategy: towards an HIV cure 2016
Steven G. Deeks,Sharon R Lewin,Anna Laura Ross,Jintanat Ananworanich,Monsef Benkirane,Paula M. Cannon,Nicolas Chomont,Daniel C. Douek,Jeffrey D. Lifson,Ying-Ru Lo,Daniel R. Kuritzkes,David M. Margolis,John W. Mellors,Deborah Persaud,Joseph D. Tucker,Françoise Barré-Sinoussi,Galit Alter,Judith D. Auerbach,Brigitte Autran,Dan H. Barouch,Georg M. N. Behrens,Marina Cavazzana,Zhiwei Chen,Éric A. Cohen,Giulio Maria Corbelli,Serge Eholié,Nir Eyal,Sarah Fidler,Laurindo Garcia,Cynthia I. Grossman,Gail E. Henderson,Timothy J. Henrich,Richard Jefferys,Hans-Peter Kiem,Joseph M. McCune,Keymanthri Moodley,Peter A. Newman,Monique Nijhuis,Moses Supercharger Nsubuga,Melanie Ott,Sarah Palmer,Douglas D. Richman,Asier Sáez-Cirión,Matthew G.F. Sharp,Janet M. Siliciano,Guido Silvestri,Jerome Amir Singh,Bruno Spire,Jeff Taylor,Martin Tolstrup,Susana T. Valente,Jan van Lunzen,Rochelle P. Walensky,Ira B. Wilson,Jerome A. Zack +54 more
TL;DR: A group of international experts to develop a scientific strategy for research towards an HIV cure summarized the group's strategy in this Perspective.