N
Nadine Thierfelder
Researcher at Max Delbrück Center for Molecular Medicine
Publications - 2
Citations - 3512
Nadine Thierfelder is an academic researcher from Max Delbrück Center for Molecular Medicine. The author has contributed to research in topics: Gene expression & Gene. The author has an hindex of 2, co-authored 2 publications receiving 3297 citations.
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Widespread changes in protein synthesis induced by microRNAs
Matthias Selbach,Björn Schwanhäusser,Nadine Thierfelder,Zhuo Fang,Raya Khanin,Nikolaus Rajewsky +5 more
TL;DR: It is shown that a single miRNA can repress the production of hundreds of proteins, but that this repression is typically relatively mild, and the data suggest that a mi RNA can, by direct or indirect effects, tune protein synthesis from thousands of genes.
Journal ArticleDOI
Conservation of mRNA and protein expression during development of C. elegans.
Dominic Grün,Marieluise Kirchner,Nadine Thierfelder,Marlon Stoeckius,Matthias Selbach,Nikolaus Rajewsky +5 more
TL;DR: It is observed that developmental mRNA and protein changes were highly conserved to a surprisingly similar degree but were poorly correlated within a species, suggesting important and widespread posttranscriptional regulation.