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Nadira Delhem
Researcher at university of lille
Publications - 66
Citations - 1318
Nadira Delhem is an academic researcher from university of lille. The author has contributed to research in topics: Immune system & Photodynamic therapy. The author has an hindex of 19, co-authored 56 publications receiving 1108 citations. Previous affiliations of Nadira Delhem include French Institute of Health and Medical Research & Pasteur Institute.
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Journal ArticleDOI
Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells
Dhafer Mrizak,Nathalie Martin,Clément Barjon,Anne-Sophie Jimenez-Pailhes,Rami Mustapha,Toshiro Niki,Joël Guigay,Véronique Pancré,Yvan de Launoit,Philippe Busson,Olivier Moralès,Nadira Delhem +11 more
TL;DR: Interactions between NPC-Exo and Treg represent a newly defined mechanism that may be involved in regulating peripheral tolerance by tumors and in supporting immune evasion in human NPC.
Journal ArticleDOI
In Vitro Effects of Cyclosporine A and Tacrolimus on Regulatory T-Cell Proliferation and Function
Céline Miroux,Olivier Moralès,Khaldoun Ghazal,Samia Ben Othman,Yvan de Launoit,Véronique Pancré,Filomena Conti,Nadira Delhem +7 more
TL;DR: Low doses of cyclosporine inhibit Treg activity, a finding that might explain the beneficial effect of this drug on hepatitis C recurrence, and by maintaining T Reg activity, tacrolimus could be more helpful than cyclospora in controlling rejection.
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Expression of hepatitis C virus NS5A natural mutants in a hepatocytic cell line inhibits the antiviral effect of interferon in a PKR-independent manner
Philippe Podevin,Abdelmajid Sabile,Rodrigo Gajardo,Nadira Delhem,Annie Abadie,Pierre-Yves Lozach,Laura Beretta,Laura Beretta,Christian Bréchot +8 more
TL;DR: The results support an important role of NS5A in controlling IFN‐α antiviral activity; they show, however, that PKR‐independent mechanisms are implicated, at least in liver‐derived cells.
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IL-23/IL-17A Axis Correlates with the Nitric Oxide Pathway in Inflammatory Bowel Disease: Immunomodulatory Effect of Retinoic Acid
Hayet Rafa,Houria Saoula,Mourad Belkhelfa,Oussama Medjeber,Imene Soufli,Ryma Toumi,Yvan de Launoit,Olivier Moralès,M’hamed Nakmouche,Nadira Delhem,Chafia Touil-Boukoffa +10 more
TL;DR: The study indicates that the IL-23/IL-17A axis plays a pivotal role in IBD pathogenesis through the NO pathway, and shows that both p-STAT3 and inducible NOS expression was upregulated in PBMCs and colonic mucosa, especially in patients with active CD.
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CCL18 differentiates dendritic cells in tolerogenic cells able to prime regulatory T cells in healthy subjects
Imane Azzaoui,Saliha Ait Yahia,Ying Chang,Han Vorng,Olivier Moralès,Ying Fan,Nadira Delhem,Coline Plé,André-Bernard Tonnel,Benoit Wallaert,Anne Tsicopoulos +10 more
TL;DR: This study is the first to define a chemokine able to generate tolerogenic DCs, however, this function was absent in allergic donors and may participate to the decreased tolerance observed in allergic diseases.