N
Nagendra K. Chaturvedi
Researcher at University of Nebraska Medical Center
Publications - 33
Citations - 486
Nagendra K. Chaturvedi is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Cell growth & Neuroblastoma. The author has an hindex of 11, co-authored 25 publications receiving 376 citations. Previous affiliations of Nagendra K. Chaturvedi include Nebraska Medical Center.
Papers
More filters
Journal ArticleDOI
Human Prostatic Acid Phosphatase: Structure, Function and Regulation
Sakthivel Muniyan,Nagendra K. Chaturvedi,Jennifer G. Dwyer,Chad A. LaGrange,William G. Chaney,Ming Fong Lin +5 more
TL;DR: Interestingly, promoter analysis suggests that PAcP expression can be regulated by NF-κB, via a novel binding sequence in an androgen-independent manner, which will have a significant impact on understanding PCa progression and therapy.
Journal ArticleDOI
Chronic lymphocytic leukemia cells in a lymph node microenvironment depict molecular signature associated with an aggressive disease
Amit K. Mittal,Nagendra K. Chaturvedi,Karan Rai,Christine E. Gilling-Cutucache,Tara M. Nordgren,Margaret Moragues,Runqing Lu,Rene Opavsky,Greg Bociek,Dennis D. Weisenburger,Javeed Iqbal,Shantaram S. Joshi +11 more
TL;DR: The findings demonstrate that the lymphoid microenvironment promotes survival, proliferation and progression of CLL cells via chronic activation of BCR, BAFF/APRIL and NF-κB activation while suppressing the immune response.
Journal ArticleDOI
Lymph node‐induced immune tolerance in chronic lymphocytic leukaemia: a role for caveolin‐1
Christine E Gilling,Amit K. Mittal,Nagendra K. Chaturvedi,Javeed Iqbal,Patricia Aoun,Philip J. Bierman,Robert G. Bociek,Dennis D. Weisenburger,Shantaram S. Joshi +8 more
TL;DR: A novel role for CAV1 in tumour‐induced immunosuppression during the progression of CLL is reported, specifically those involved in actin polymerization.
Journal ArticleDOI
Role of CTLA4 in the Proliferation and Survival of Chronic Lymphocytic Leukemia
Amit K. Mittal,Nagendra K. Chaturvedi,Rae A. Rohlfsen,Payal Gupta,Avadhut D. Joshi,Ganapati V. Hegde,R. Gregory Bociek,Shantaram S. Joshi +7 more
TL;DR: Results indicate that microenvironment-controlled-CTLA4 expression mediates proliferation/survival of CLL cells by regulating the expression/activation of STAT1, NFATC2, c-Fos,c-Myc, and/or Bcl-2.
Journal ArticleDOI
Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells.
Yu Wei Chou,Nagendra K. Chaturvedi,Shougiang Ouyang,Fen Fen Lin,Dharam Kaushik,Jue Wang,Isaac Yi Kim,Ming Fong Lin +7 more
TL;DR: In this article, the molecular target by histone deacetylase (HDAC) inhibitors for exploring their potential prostate cancer (PCa) therapy was identified, correlating with increased cellular prostatic acid phosphatase (cPAcP) expression.