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Nan Li
Researcher at Peking University
Publications - 4
Citations - 760
Nan Li is an academic researcher from Peking University. The author has contributed to research in topics: Hybrid genome assembly & DNA sequencing theory. The author has an hindex of 4, co-authored 4 publications receiving 619 citations.
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Estimation of genomic characteristics by analyzing k-mer frequency in de novo genome projects
Binghang Liu,Yujian Shi,Jianying Yuan,Xuesong Hu,Hao Zhang,Nan Li,Zhenyu Li,Yanxiang Chen,Desheng Mu,Wei Fan +9 more
TL;DR: The k-mer frequency analysis can be used as a general and assembly-independent method for estimating genomic characteristics, which can improve the understanding of a species genome, help design the sequencing strategy of genome projects, and guide the development of assembly algorithms.
Journal ArticleDOI
Comparison of the two major classes of assembly algorithms: overlap-layout-consensus and de-bruijn-graph.
Zhenyu Li,Yanxiang Chen,Desheng Mu,Jianying Yuan,Yujian Shi,Hao Zhang,Jun Gan,Nan Li,Xuesong Hu,Binghang Liu,Bicheng Yang,Wei Fan +11 more
TL;DR: A detailed comparison of the two major classes of assembly algorithms: overlap-layout-consensus and de-bruijn-graph is made, from how they match the Lander-Waterman model, to the required sequencing depth and reads length.
Journal ArticleDOI
pIRS: Profile-based Illumina pair-end reads simulator
Xuesong Hu,Jianying Yuan,Yujian Shi,Jianliang Lu,Binghang Liu,Zhenyu Li,Yanxiang Chen,Desheng Mu,Hao Zhang,Nan Li,Zhen Yue,Fan Bai,Heng Li,Wei Fan +13 more
TL;DR: A software package, pIRS (profile-based Illumina pair-end reads simulator), which simulates Illumina reads with empirical Base-Calling and GC%-depth profiles trained from real re-sequencing data, fits the properties of real sequencing data better than existing simulators.
Comparison of the two major classes of assembly algorithms: overlap^layout^consensus and
TL;DR: A detailed comparison of the two major classes of assembly algorithms, overlap and de-bruijn-graph, from how they match the Lander^Waterman model, to the required sequencing depth and reads length, is presented in this paper.